Objective. To assess safety and clinical outcomes in patients with inflammatory arthritis after
intraarticular (IA) injection of rAAV2-TNFR:Fc, a recombinant adeno-associated viral vector …

Serum muscle enzyme levels are usually elevated in patients with untreated polymyositis
and dermatomyositis. Creatine kinase is the muscle enzyme most often used to diagnose …

Objective. To compare the relative safety and efficacy of azathioprine (AZA), methotrexate (MTX),
and the combination of both in the treatment of active rheumatoid arthritis (RA). Methods…

… Fudman's work was supported by grant T32-AM-07080 from the NIADDK. Dr. Barkan is
the recipient of the Career Development Research Associate Award from the VA Medical …

Certain synthetic N-formylated peptides are potent chemotactic agents for phagocytic cells.
We have identified a specific, high affinity receptor for the chemotactic peptide fMet-Leu-[3H]…

Scleromyxedema is an infiltrative skin disease produced by hyaluronic acid deposition in
the dermis. A benign monoclonal gammopathy is usually present. We report 2 patients with …

By Edward J. Fudman and Thomas J. Schnitzer P OLYMYOSITIS(PM) and dermatomyositis (DM)
are inflammatory muscle diseases of unknown etiology. There is strong evidence for …

Objective. To assess the validity, responsiveness, and reliability of single-joint outcome
measures for determining target joint (TJ) response in patients with inflammatory arthritis. …

Eleven patients with rheumatoid arthritis (RA) were treated with intraarticular deferoxamine
or placebo to test the hypothesis that iron chelation decreased hydroxyl radical mediated …

A 64-year-old woman with systemic sclerosis and pulmonary hypertension underwent Swan-Ganz
catheterization to test her response to the calcium channel blocker nifedipine. …