Multiple common variants for celiac disease influencing immune gene expression

…, LH Van Den Berg, NA Bockett, EG De La Concha… - Nature …, 2010 - nature.com
We performed a second-generation genome-wide association study of 4,533 individuals with
celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with …

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

…, G Castillejo, EG De La Concha, RC de Almeida… - Nature …, 2011 - nature.com
Using variants from the 1000 Genomes Project pilot European CEU dataset and data from
additional resequencing studies, we densely genotyped 183 non-HLA risk loci previously …

Myenteric antiplexus antibodies and class II HLA in achalasia

…, A Figueredo, M Díaz-Rubio, EG De-la-Concha - Digestive diseases and …, 2002 - Springer
Achalasia, a motor disorder of the esophagus, is accompanied by autoimmune phenomena
that could be playing a role in the pathogenesis of the disease. Our objective was to …

Association of the STAT4 gene with increased susceptibility for some immune‐mediated diseases

…, EG De La Concha… - Arthritis & …, 2008 - Wiley Online Library
Objective The STAT4 gene encodes a transcription factor involved in the signaling
pathways of several cytokines, including interleukin‐12 (IL‐12), the type I interferons, and IL‐23. …

HLA-DQ2-negative celiac disease in Finland and Spain

…, C Calvo, C Maluenda, P Westman, EG de la Concha… - Human immunology, 1998 - Elsevier
… For example, the Spanish patients who developed CD during their adulthood (eg, 1440D
and 1947D) had the typical Spanish markers, rather than DR4 DQ8. On the other hand, …

PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population

…, B Fernandez-Gutierrez, EG De La Concha… - …, 2005 - academic.oup.com
EG de la Concha , EG de la Concha … obtained according to the Declaration of Helsinki,
and the research was approved by the ethical committees of the Clinico and La Paz hospitals. …

Changes in IgM and IgG antibody concentrations in brucellosis over time: importance for diagnosis and follow-up

…, M Baquero, J Gil, EG de la Concha - Journal of infectious …, 1989 - academic.oup.com
Abstract Changes in concentrations of IgM and IgG antibodies to Brucella were monitored
for at least 13 mo by an enzyme-linked immunosorbent assay (ELISA) in 52 patients with …

Development of splenic natural suppressor (NS) cells in Ehrlich tumor‐bearing mice

…, J Gil, MA Figueredo, EG de la Concha - … journal of cancer, 1989 - Wiley Online Library
… A striking decrease in the response to Con A and LPS mitogens by spleen cells of ET-bearing …
and DE LA CONCHA, EG, IgM response and resistance to ascites tumor growth. Cancer …

IL23R: a susceptibility locus for celiac disease and multiple sclerosis?

…, V De Las Heras, M Bartolomé, EG De La Concha… - Genes & …, 2008 - nature.com
Recent studies have shown association of the IL23R gene with inflammatory bowel disease,
psoriasis and ankylosing spondylitis. We aimed at studying the involvement of IL23R in …

Histones interact with anionic phospholipids with high avidity; its relevance for the binding of histone‐antihistone immune complexes

…, A Caturla, A Bustos, EGDL Concha… - Clinical & …, 1994 - Wiley Online Library
Antibodies recognizing anionic phospholipids have been described in systemic lupus
erythematosus (SLE) and other autoimmune diseases. Recent studies have shown that some of …