… EC LeRoy, Department of Microbiology and Immunology, Medical University of South
Carolina, 173 Ashley Avenue, PO Box 250504, Charleston, SC 29425. E-mail: leroyc@musc.edu …

Major confusion exists with regard to the definition of patients with Raynaud's phenomenon;
defining the patient and the phenomenon are reasonably straightforward, but variations in …

… or along with EC perturbation is unknown; certainly EC changes, at … to EC abnormalities is
unknown; certainly subcutaneous inflammation (eg photoinjury) can occur without residual EC …

A subclassification of SSc patients is proposed by a group of experienced investigators. The
subsets are defined by skin involvement with limited cutaneous SSc (lcSSc) patients having …

Cultures of dividing skin fibroblasts from normal and sclerodermatous human skin have
permitted estimations of soluble collagen concentration, net collagen accumulation, cell-…

Background— Information is limited regarding the rates of progression to congestive heart
failure (CHF) and death in individuals with asymptomatic left ventricular systolic dysfunction (…

… Cannon PJ, Hassar M, Case DB, Casarella WJ, Sommers SC, LeRoy EC: … Maricq HR, LeRoy
EC: Patterns of finger capillary ab… Maricq HR, Spencer-Green G, LeRoy EC: Skin capillary …

Objective To develop and test a severity scale for individual organ involvements in systemic
sclerosis (SSc, scleroderma). Methods An international study group completed the following …

Scleroderma (progressive systemic sclerosis) is a disease of unknown etiology characterized
by widespread alterations of connective tissue and by vascular lesions in many organs (S1)…

In vivo capillary examination was performed on 80 patients included in a prospective study
of Raynaud phenomenon (RP): 40 RP only (RPO), 20 undifferentiated connective tissue …