In spite of substantial efforts by many investigators as well as numerous publications on the
subject, the nomenclature of the systemic vasculitides remains enigmatic. A major problem is …

Antineutrophil cytoplasmic antibody (ANCA) tests are used to diagnose and monitor
inflammatory activity in Wegener granulomatosis, microscopic polyangiitis and its renal-limited …

Background The primary systemic vasculitides usually associated with autoantibodies to
neutrophil cytoplasmic antigens include Wegener's granulomatosis and microscopic polyangiitis…

… The correlation coefficient for the results obtained in the center of origin and the central
laboratory for the assays was 0.94 (Copenhagen PR-3), 0.83 (Raisdorf PR3), 0.84 (Leiden PR3) …

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is the most common
cause of rapidly progressive glomerulonephritis worldwide, and the renal biopsy is the gold …

Results The validation study showed that kidney failure at 10-year follow-up was significantly
different between the histopathologic classes (P< 0.001). Kidney failure at 10-year follow-…

… Dadoniené (University Hospital Vilnius, Vilnius, Lithuania), EC Hagen (Eemland Hospital,
Amersfoort, The Netherlands), CGM Kallenberg, C. Stegeman (University Hospital Groningen, …

Until recently, intravenous cyclophosphamide pulses with oral corticosteroids were regarded
standard therapy for proliferative lupus nephritis (LN). Azathioprine, a less toxic alternative, …

… Dadoniené (University Hospital Vilnius, Lithuania); EC Hagen (Eemland Hospital, Amersfoort,
The Netherlands); CGM Kallenberg and C. Stegeman (University Hospital Groningen, The …

Background Granulomatosis with polyangiitis (Wegener's) (GPA) and microscopic
polyangiitis (MPA) are subgroups of anti-neutrophil cytoplasmic antibody (ANCA)-associated …