[BOOK][B] Foundations of optimal control theory
EB Lee, L Markus - 1967 - apps.dtic.mil
This complete and authoritative presentation of the current status of control theory offers a
useful foundation for both study and research. With emphasis on general nonlinear differential …
useful foundation for both study and research. With emphasis on general nonlinear differential …
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and …
Our understanding of Alzheimer’s disease (AD) pathophysiology remains incomplete. Here
we used quantitative mass spectrometry and coexpression network analysis to conduct the …
we used quantitative mass spectrometry and coexpression network analysis to conduct the …
Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis
…, EM Wood, Y Baek, L Kwong, EB Lee… - Annals of …, 2013 - Wiley Online Library
Objective To see whether the distribution patterns of phosphorylated 43kDa TAR DNA‐binding
protein (pTDP‐43) intraneuronal inclusions in amyotrophic lateral sclerosis (ALS) permit …
protein (pTDP‐43) intraneuronal inclusions in amyotrophic lateral sclerosis (ALS) permit …
SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
Recent advances in spatially resolved transcriptomics (SRT) technologies have enabled
comprehensive characterization of gene expression patterns in the context of tissue …
comprehensive characterization of gene expression patterns in the context of tissue …
[HTML][HTML] Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
…, R Fleischmann, S Cohen, EB Lee… - … England Journal of …, 2012 - Mass Medical Soc
Background Tofacitinib (CP-690,550) is a novel oral Janus kinase inhibitor that is being
investigated for the treatment of rheumatoid arthritis. Methods In this 12-month, phase 3 trial, 717 …
investigated for the treatment of rheumatoid arthritis. Methods In this 12-month, phase 3 trial, 717 …
[HTML][HTML] Tofacitinib versus methotrexate in rheumatoid arthritis
EB Lee, R Fleischmann, S Hall… - … England Journal of …, 2014 - Mass Medical Soc
Background Methotrexate is the most frequently used first-line antirheumatic drug. We report
the findings of a phase 3 study of monotherapy with tofacitinib, an oral Janus kinase inhibitor…
the findings of a phase 3 study of monotherapy with tofacitinib, an oral Janus kinase inhibitor…
Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
RNA-binding proteins, and in particular TAR DNA-binding protein 43 (TDP43), are central to
the pathogenesis of motor neuron diseases and related neurodegenerative disorders. …
the pathogenesis of motor neuron diseases and related neurodegenerative disorders. …
Can autism be diagnosed accurately in children under 3 years?
WL Stone, EB Lee, L Ashford, J Brissie… - The Journal of Child …, 1999 - cambridge.org
This study investigated the reliability and stability of an autism diagnosis in children under 3
years of age who received independent diagnostic evaluations from two clinicians during …
years of age who received independent diagnostic evaluations from two clinicians during …
Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci
…, N Ito, J Kera, E Okada, K Yatsu, YW Song, EB Lee… - Nature …, 2010 - nature.com
Behçet's disease is a chronic systemic inflammatory disorder characterized by four major
manifestations: recurrent ocular symptoms, oral and genital ulcers and skin lesions 1 . We …
manifestations: recurrent ocular symptoms, oral and genital ulcers and skin lesions 1 . We …
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
Accumulation of hyperphosphorylated, ubiquitinated and N-terminally truncated TAR DNA-binding
protein (TDP-43) is the pathological hallmark lesion in most familial and sporadic …
protein (TDP-43) is the pathological hallmark lesion in most familial and sporadic …