Convenient single-step, one tube purification of PCR products for direct sequencing.

E Werle, C Schneider, M Renner, M Völker… - Nucleic acids …, 1994 - ncbi.nlm.nih.gov
Arg'58) are encoded by three co-dominant alleles (E2, e3, e4). Phenotyping is cumbersome
and, therefore, several methods for apo E genotyping have been developed. Of these, PCR-…

Recent bacterial and viral infection is a risk factor for cerebrovascular ischemia: clinical and biochemical studies

…, E Zimmermann, M Spiel, T Fent, M Maiwald, E Werle… - Neurology, 1998 - AAN Enterprises
We performed a case-control study to investigate the role of recent infection as stroke risk
factor and to identify pathogenetic pathways linking infection and stroke. We examined 166 …

Association of cervical artery dissection with recent infection

…, F Buggle, E Orberk, J Mytilineos, E Werle… - Archives of …, 1999 - jamanetwork.com
Background Cervical artery dissection (CAD) is an important cause of ischemic stroke in
younger patients. However, its cause is insufficiently understood. Objective To test the …

Plasma levels of asymmetrical dimethyl-L-arginine in patients with congenital heart disease and pulmonary hypertension

M Gorenflo, C Zheng, E Werle, W Fiehn… - Journal of …, 2001 - journals.lww.com
Asymmetrical dimethyl-l-arginine (ADMA) is an endogenous inhibitor of nitric oxide synthase.
We hypothesized that plasma levels of ADMA could be increased in patients with …

Cerebrospinal fluid Aβ42 is increased early in sporadic Alzheimer's disease and declines with disease progression

…, N Ida, H Basun, LO Wahlund, E Werle… - Annals of Neurology …, 1999 - Wiley Online Library
… High cerebrospinal fluid tau and low amyloid 42 levels in the clinical diagnosis of Alzheimer
disease and relation to apolipoprotein E genotype. Arch Neurol 1998;55:937–945 …

The association of leukocyte count, fibrinogen and C-reactive protein with vascular risk factors and ischemic vascular diseases

AJ Grau, F Buggle, H Becher, E Werle, W Hacke - Thrombosis research, 1996 - Elsevier
In 154 subjects (age 63±11 years; 63 women and 91 men) randomly selected from the
population, we tested the hypothesis that inflammatory parameters are associated with vascular …

Effects of iron supplementation on total body hemoglobin during endurance training at moderate altitude

B Friedmann, J Jost, E Weller, E Werle… - … journal of sports …, 1999 - thieme-connect.com
1111 The aim of the study was to test the hypothesis that iron supplementation in well-trained
non-iron-depleted athletes leads to an enhanced increase of total body hemoglobin (TBH) …

Clinical and biochemical analysis in infection-associated stroke

…, T Banerjee, R Seitz, R Winter, M Forsting, E Werle… - Stroke, 1995 - Am Heart Assoc
Background and Purpose Currently, recent infection (primarily bacterial infection) is discussed
as a risk factor for cerebrovascular ischemia. The aim of this study was to investigate …

Protease inhibitors

H Fritz, I Trautschold, E Werle - Methods of enzymatic analysis, 1974 - Elsevier
… In the trypsin assay the extinction increases from E = 0.065 to E = 0.250 are proportional
to the amount of enzyme added (1–4 μg.); in the plasmin assay between E = 0.100 and E = …

Monocyte function and plasma levels of interleukin-8 in acute ischemic stroke

AJ Grau, A Reis, F Buggle, A Al-Khalaf, E Werle… - Journal of the …, 2001 - Elsevier
Activated monocytes may contribute to the pathogenesis of ischemic stroke. We tested the
hypothesis that release products and procoagulant activity of monocytes are increased in …