User profiles for Donald C. Vinh
 | Donald VinhMcGill University Health Centre Verified email at mcgill.ca Cited by 18459 |
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
…, KE Stockerl-Goldstein, S Subbiah, DC Vinh… - The Lancet, 2020 - thelancet.com
Background Data on patients with COVID-19 who have cancer are lacking. Here we characterise
the outcomes of a cohort of patients with cancer and COVID-19 and identify potential …
the outcomes of a cohort of patients with cancer and COVID-19 and identify potential …
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
…, D Van De Beek, L Roussel, DC Vinh… - Science, 2020 - science.org
INTRODUCTION Interindividual clinical variability is vast in humans infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from silent infection to rapid …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from silent infection to rapid …
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
INTRODUCTION Clinical outcomes of human severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…
[HTML][HTML] Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance
Severe acute respiratory syndrome coronavirus 2 causes direct damage to the airway
epithelium, enabling aspergillus invasion. Reports of COVID-19-associated pulmonary …
epithelium, enabling aspergillus invasion. Reports of COVID-19-associated pulmonary …
Anti-tumour necrosis factor agents and tuberculosis risk: mechanisms of action and clinical management
…, S Manners, E Skamene, R Long, DC Vinh - The Lancet infectious …, 2003 - thelancet.com
Cases of active tuberculosis have been reported worldwide with the use of therapeutic
agents that inhibit tumour necrosis factor (TNF) α. TNFα has a central role in mycobacterial …
agents that inhibit tumour necrosis factor (TNF) α. TNFα has a central role in mycobacterial …
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
The syndrome of monocytopenia, B-cell and NK-cell lymphopenia, and mycobacterial,
fungal, and viral infections is associated with myelodysplasia, cytogenetic abnormalities, …
fungal, and viral infections is associated with myelodysplasia, cytogenetic abnormalities, …
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
…, F Morandeira, L Roussel, DC Vinh… - Science …, 2021 - science.org
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
…, L Roussel, DC Vinh, C Erikstrup… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
DC Vinh, SY Patel, G Uzel, VL Anderson… - Blood, The Journal …, 2010 - ashpublications.org
We identified 18 patients with the distinct clinical phenotype of susceptibility to disseminated
nontuberculous mycobacterial infections, viral infections, especially with human …
nontuberculous mycobacterial infections, viral infections, especially with human …
[PDF][PDF] A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection
SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent
infection to lethal disease. The role of human genetics in determining clinical response to …
infection to lethal disease. The role of human genetics in determining clinical response to …