Objective The 1980 American College of Rheumatology (ACR) classification criteria for
systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present …

Systemic sclerosis, also called scleroderma, is an immune-mediated rheumatic disease that
is characterised by fibrosis of the skin and internal organs and vasculopathy. Although …

Background A phase 2 trial of tocilizumab showed preliminary evidence of efficacy in systemic
sclerosis. We assessed skin fibrosis and systemic sclerosis-associated interstitial lung …

Systemic sclerosis (SSc) is a complex, multiorgan, autoimmune disease. Lung fibrosis occurs
in ∼80% of patients with SSc; 25% to 30% develop progressive interstitial lung disease (…

Objective To develop new classification criteria for systemic lupus erythematosus ( SLE )
jointly supported by the European League Against Rheumatism ( EULAR ) and the American …

Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure ≥25 mm Hg
at rest, measured during right heart catheterization. There is still insufficient evidence to add …

The American College of Rheumatology (ACR) most recently published recommendations
for the use of diseasemodifying antirheumatic drugs (DMARDs) and biologic agents in the …

Gout is a disorder that manifests as a spectrum of clinical and pathologic features built on a
foundation of an excess body burden of uric acid, manifested in part by hyperuricemia, which …

Objective Remission in rheumatoid arthritis (RA) is an increasingly attainable goal, but there
is no widely used definition of remission that is stringent but achievable and could be …

Objective To provide guidance for the management of gout, including indications for and
optimal use of urate‐lowering therapy ( ULT ), treatment of gout flares, and lifestyle and other …