Imatinib is the treatment of choice for FIP1L1/PDGFRA (F/P)-associated chronic eosinophilic
leukemia (F/P+ CEL), but its optimal dosing, duration, and possibility of discontinuation are …

Animal models of autoimmune diseases such as experimental autoimmune encephalomyelitis
(EAE) are inflammatory demyelinating diseases which comprise a heterogeneous group …

Myelin antigen targets that are clearly associated with pathogenic events in multiple sclerosis
(MS) patients remain to be defined. We recently demonstrated that the analysis of global …

Methods. Self-IgG reactivity against normal and injured human brain tissues was studied by
Western blotting of sera from 169 subjects, 16 patients with NPSLE, 12 patients with SLE …

To date, none of the myelin-associated Ag targets definitively discriminates between the
immune response observed in multiple sclerosis (MS) patients and healthy subjects. However, it …

Apolipoprotein E (Apo E), one of the major structural and functional apolipoproteins, has
recently been implicated in the pathogenesis of Alzheimer's disease (AD). Several studies …

Background Plasmodium falciparum infections could lead to severe malaria, principally in
non-immune individuals as children and travellers from countries exempted of malaria. Severe …

OBJECTIVE: To investigate the diagnostic value of autoantibodies against alpha-fodrin in
patients with Sjögren's syndrome (SS) with neurological manifestations compared to SS …

8. Olsson T. 1995. Critical influences of the cytokine orchestration on the outcome of myelin
antigen-specific T cell autoimmunity in experimental autoimmune encephalomyelitis and …

Background and Purpose Selective agonists of the sigma‐1 receptor (σ1 protein) are
generally reported to protect against neuronal damage and modulate oligodendrocyte …