GM-CSF and M-CSF (CSF-1) induce different phenotypic changes in macrophage lineage
populations. The nature, extent, and generality of these differences were assessed by …

Data from preclinical and clinical studies have demonstrated that granulocyte macrophage
colony-stimulating factor (GM-CSF) can function as a key proinflammatory cytokine. However, …

Introduction Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been shown
to be important in the development of inflammatory models of rheumatoid arthritis and there …

Chronic hepatic inflammation from multiple etiologies leads to a fibrogenic response that
can progress to cirrhosis and liver failure. Transplantation of human amniotic epithelial cells (…

Objective The hyperplasia of fibroblast‐like synoviocytes (FLS) is considered essential to
the evolution of joint destruction in rheumatoid arthritis (RA), but the mechanisms underlying …

Objective To study the capacity of macrophage migration inhibitory factor (MIF) to regulate
proliferation, apoptosis, and p53 in an animal model of rheumatoid arthritis (RA) and in …

Objectives Better therapies are needed for inflammatory pain. In arthritis the relationship
between joint pain, inflammation and damage is unclear. Granulocyte-macrophage colony-…

M-CSF (or CSF-1) and GM-CSF can regulate the development and function of the mononuclear
phagocyte system (MPS). To address some of the outstanding and sometimes conflicting …

Macrophage migration inhibitory factor (MIF) has a key role in regulation of innate and
adaptive immunity and is implicated in sepsis, tumorigenesis, and autoimmune disease. MIF …

TNF and granulocyte macrophage-colony stimulating factor (GM-CSF) have proinflammatory
activity and both contribute, for example, to rheumatoid arthritis pathogenesis. We …