User profiles for David Simon

David K. Simon

- Verified email at bidmc.harvard.edu - Cited by 12909

David Simon

- Verified email at rhul.ac.uk - Cited by 9475

David J. Simon

- Verified email at med.cornell.edu - Cited by 3097

[BOOK][B] Elite deviance

D Simon - 2018 - taylorfrancis.com
Tracing the causes of elite deviance to the structure of US power and wealth, this book
introduces students to theories of elite deviance and covers both criminal and non-criminal elite …

Urban land teleconnections and sustainability

…, DK Munroe, B Olah, D Simon - Proceedings of the …, 2012 - National Acad Sciences
This paper introduces urban land teleconnections as a conceptual framework that explicitly
links land changes to underlying urbanization dynamics. We illustrate how three key themes …

Urban environments: issues on the peri-urban fringe

D Simon - Annual review of environment and resources, 2008 - annualreviews.org
This chapter reviews current thinking about environment-development issues in the transitional
zones between distinctly urban and unambiguously rural areas, known variously as rural-…

Human hypertension caused by mutations in WNK kinases

…, B Dussol, Y Berland, RJ Unwin, H Mayan, DB Simon… - Science, 2001 - science.org
Hypertension is a major public health problem of largely unknown cause. Here, we identify
two genes causing pseudohypoaldosteronism type II, a Mendelian trait featuring hypertension…

[HTML][HTML] Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

…, C Handschin, K Zheng, J Lin, W Yang, DK Simon… - Cell, 2006 - cell.com
PPARγ coactivator 1α (PGC-1α) is a potent stimulator of mitochondrial biogenesis and
respiration. Since the mitochondrial electron transport chain is the main producer of reactive …

Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg2+ Resorption

DB Simon, Y Lu, KA Choate, H Velazquez… - Science, 1999 - science.org
Epithelia permit selective and regulated flux from apical to basolateral surfaces by transcellular
passage through cells or paracellular flux between cells. Tight junctions constitute the …

Gitelman's variant of Barter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na–Cl cotransporter

DB Simon, C Nelson-Williams, M Johnson Bia… - Nature …, 1996 - nature.com
Maintenance of fluid and electrolyte homeostasis is critical for normal neuromuscular
function. Bartter's syndrome is an autosomal recessive disease characterized by diverse …

[HTML][HTML] iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging

N Renier, Z Wu, DJ Simon, J Yang, P Ariel… - Cell, 2014 - cell.com
The visualization of molecularly labeled structures within large intact tissues in three
dimensions is an area of intense focus. We describe a simple, rapid, and inexpensive method, …

Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na–K–2CI cotransporter NKCC2

DB Simon, FE Karet, JM Hamdan, AD Pietro… - Nature …, 1996 - nature.com
Inherited hypokalaemic alkalosis with low blood pressure can be divided into two groups —
Gitelman's syndrome, featuring hypocalciuria, hypomagnesaemia and milder clinical …

[HTML][HTML] Trial of cinpanemab in early Parkinson's disease

…, CM Tanner, RB Postuma, DK Simon… - … England Journal of …, 2022 - Mass Medical Soc
Background Aggregated α-synuclein plays an important role in Parkinson’s disease
pathogenesis. Cinpanemab, a human-derived monoclonal antibody that binds to α-synuclein, is …