During the 1980s CD46 was discovered in a search for C3b binding proteins of human
peripheral blood cells. Its role as an inactivator of C3b and C4b deposited on self-tissue is …

Toxoplasma gondii undergoes differentiation from rapidly growing tachyzoites to slowly growing
bradyzoites during its life cycle in the intermediate host, and conversion can be induced …

Objective To evaluate whether tocilizumab ( TCZ ) monotherapy is noninferior to treatment
with TCZ plus methotrexate ( MTX ) for maintaining clinical responses in patients with …

Membrane cofactor protein (MCP or CD46), a widely distributed complement regulatory
human protein, is a cell surface receptor for many pathogens including group A streptococci (…

Human membrane cofactor protein (CD46) protects host cells against complement attack
and may function as a receptor for pathogenic Neisseriae. We assessed CD46 expression in …

CD46 is a complement regulator that serves as a cellular pilus receptor for the human
pathogens Neisseria gonorrhoeae and Neisseria meningitidis. The role of CD46 in N. …

Following attachment of Neisseria gonorrhoeae to human epithelial cell lines, the cellular
pilus receptor CD46 is shed from the cell and accumulates in the media. In this report, we …

Chronic graft-versus-host disease (cGVHD) and its management with immunosuppressive
therapies increase the susceptibility to severe acute respiratory syndrome coronavirus 2 (…

Objective. To assess differences in joint damage and inflammation using magnetic resonance
imaging (MRI) between patients with rheumatoid arthritis (RA) who achieved low disease …

The effect of sodium azide and antimycin on the production of psittacosis organisms from L
cells was studied. In both cases it was found that a reduction of cellular adenosine …