User profiles for Dafna D Gladman

Dafna Gladman

Professor of Medicine
Verified email at utoronto.ca
Cited by 129541

Derivation of the SLEDAI. A disease activity index for lupus patients

…, DD Gladman, MB Urowitz, D Caron… - … : Official Journal of …, 1992 - Wiley Online Library
Objective. To standardize outcome measures in systemic lupus erythematosus (SLE). Three
indices were identified which could adequately describe outcome (disease activity, damage …

Systemic lupus erythematosus disease activity index 2000.

DD Gladman, D Ibanez, MB Urowitz - The Journal of rheumatology, 2002 - jrheum.org
OBJECTIVE: To describe the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K),
a modification of SLEDAI to reflect persistent, active disease in those descriptors …

2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus

…, B Diamond, DD Gladman… - Arthritis & …, 2019 - Wiley Online Library
Objective To develop new classification criteria for systemic lupus erythematosus ( SLE )
jointly supported by the European League Against Rheumatism ( EULAR ) and the American …

Methods for assessing responsiveness: a critical review and recommendations

…, RJ Cook, VT Farewell, DD Gladman - Journal of clinical …, 2000 - Elsevier
A review of the literature suggests there are two major aspects of responsiveness. We
define the first as “internal responsiveness,” which characterizes the ability of a measure to …

Mortality in systemic lupus erythematosus

…, S Manzi, E Ginzler, DD Gladman… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To examine mortality rates in the largest systemic lupus erythematosus (SLE) cohort
ever assembled. Methods Our sample was a multisite international SLE cohort (23 centers…

Psoriatic arthritis

…, RA Colbert, DD Gladman - New England Journal of …, 2017 - Mass Medical Soc
Psoriatic arthritis occurs in up to 30% of people with psoriasis and can have serious
debilitating effects on the peripheral joints, spine, tendon insertions, and fingers …

Adalimumab for the treatment of patients with moderately to severely active psoriatic arthritis: results of a double‐blind, randomized, placebo‐controlled trial

PJ Mease, DD Gladman, CT Ritchlin… - … : Official Journal of …, 2005 - Wiley Online Library
Objective Adalimumab, a fully human, anti–tumor necrosis factor monoclonal antibody, was
evaluated for its safety and efficacy compared with placebo in the treatment of active …

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

…, V Chandran, CF Rosen, P Rahman, DD Gladman… - Nature …, 2012 - nature.com
To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis
of 3 genome-wide association studies (GWAS) and 2 independent data sets genotyped …

Group for research and assessment of psoriasis and psoriatic arthritis 2015 treatment recommendations for psoriatic arthritis

…, LR Espinoza, O FitzGerald, DD Gladman… - Arthritis & …, 2016 - Wiley Online Library
Objective To update the 2009 Group for Research and Assessment of Psoriasis and Psoriatic
Arthritis (GRAPPA) treatment recommendations for the spectrum of manifestations affecting …

Psoriatic arthritis (PSA)-an analysis of 220 patients

DD Gladman, R Shuckett, ML Russell… - … Journal of Medicine, 1987 - academic.oup.com
Since 1978, 220 patients with psoriatic arthritis have undergone detailed study at the Women's
College Hospital in Toronto, Canada. Clinical, radiological and biochemical data were …