User profiles for DAVID A. ELASHOFF

David Elashoff

Professor of Medicine, Biostatistics, and Computational Medicine, UCLA
Verified email at ucla.edu
Cited by 38660

PD-1 blockade induces responses by inhibiting adaptive immune resistance

…, RO Emerson, H Robins, RH Pierce, DA Elashoff… - Nature, 2014 - nature.com
Therapies that target the programmed death-1 (PD-1) receptor have shown unprecedented
rates of durable clinical responses in patients with various cancer types 1 , 2 , 3 , 4 , 5 . One …

[HTML][HTML] Completion dissection or observation for sentinel-node metastasis in melanoma

…, HJ Wang, DA Elashoff, RM Elashoff - … England Journal of …, 2017 - Mass Medical Soc
Background Sentinel-lymph-node biopsy is associated with increased melanoma-specific
survival (ie, survival until death from melanoma) among patients with node-positive …

[HTML][HTML] Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement

…, I Yip, JM Ashley, DA Elashoff, RM Elashoff… - The American journal of …, 1999 - Elsevier
Background We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice
supplement in an American population consuming a diet similar to the American Heart …

Surgery for papillary thyroid carcinoma: is lobectomy enough?

AH Mendelsohn, DA Elashoff… - … –head & neck …, 2010 - jamanetwork.com
… Drafting of the manuscript: Mendelsohn, Elashoff, and St John. Critical revision of the
manuscript for important intellectual content: Elashoff, Abemayor, and St John. Statistical analysis: …

[HTML][HTML] Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling

…, AT Chon, AE Hegab, T Grogan, DA Elashoff… - Cell stem cell, 2014 - cell.com
Airways are exposed to myriad environmental and damaging agents such as reactive oxygen
species (ROS), which also have physiological roles as signaling molecules that regulate …

Phase I Trial of Intratumoral Injection of CCL21 Gene–Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8+ T-cell Infiltration

…, G Lee, WD Wallace, S Lee, G Zeng, DA Elashoff… - Clinical Cancer …, 2017 - AACR
Purpose: A phase I study was conducted to determine safety, clinical efficacy, and antitumor
immune responses in patients with advanced non–small cell lung carcinoma (NSCLC) …

Comorbidities are associated with poorer outcomes in community patients with rheumatoid arthritis

VK Ranganath, P Maranian, DA Elashoff… - …, 2013 - academic.oup.com
Objective. To evaluate the impact of comorbidities on achieving remission by examining
changes in the clinical disease activity index (CDAI) in RA patients in the community-based …

[HTML][HTML] Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino …

…, A Chu, K Kempf, C Janzen, T Grogan, DA Elashoff… - Plos one, 2017 - journals.plos.org
Placental insufficiency leading to intrauterine growth restriction (IUGR) demonstrates perturbed
gene expression affecting placental angiogenesis and nutrient transfer from mother to …

Snail Promotes CXCR2 LigandDependent Tumor Progression in NonSmall Cell Lung Carcinoma

…, V Mah, D Chia, L Goodglick, DA Elashoff… - Clinical Cancer …, 2009 - AACR
Purpose: As a transcriptional repressor of E-cadherin, Snail has predominantly been
associated with epithelial-mesenchymal transition, invasion, and metastasis. However, other …

Histopathologic findings of HPV and p16 positive HNSCC

…, CK Lai, IP Shintaku, DA Elashoff… - The …, 2010 - Wiley Online Library
Objective: Human papilloma virus (HPV) and p16INKa (p16) positivity in head and neck
squamous cell carcinomas (HNSCCs) is currently thought to be an encouraging prognostic …