[HTML][HTML] Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis
…, A Six, F Carrat, V Thibault, D Sene… - … England Journal of …, 2011 - Mass Medical Soc
Background Patients with vasculitis induced by the hepatitis C virus (HCV) have reduced levels
of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of vasculitis …
of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of vasculitis …
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
…, J Tanaka, D Dalmau, PL Tharaux, D Sene… - Science …, 2021 - science.org
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
…, D Dalmau, PL Tharaux, D Sene… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …
Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with …
A Mathian, M Mahevas, J Rohmer… - Annals of the …, 2020 - ard.bmj.com
The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
disease 2019 (COVID-19) represents a source of concern for the management of patients with …
disease 2019 (COVID-19) represents a source of concern for the management of patients with …
Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial
…, J Morel, G Hayem, P Hatron, A Perdriger, D Sene… - Jama, 2014 - jamanetwork.com
Importance Primary Sjögren syndrome is a systemic autoimmune disease characterized by
mouth and eye dryness, pain, and fatigue. Hydroxychloroquine is the most frequently …
mouth and eye dryness, pain, and fatigue. Hydroxychloroquine is the most frequently …
Rituximab plus Peg-interferon-α/ribavirin compared with Peg-interferon-α/ribavirin in hepatitis C–related mixed cryoglobulinemia
D Saadoun, M Resche Rigon, D Sene… - Blood, The Journal …, 2010 - ashpublications.org
Abstract Treatment of hepatitis C (HCV)–mixed cryoglobulinemia (MC) may target either the
viral trigger (HCV) or the downstream B-cell clonal expansion. Prospective cohort study of …
viral trigger (HCV) or the downstream B-cell clonal expansion. Prospective cohort study of …
[HTML][HTML] PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma
A Beldi-Ferchiou, M Lambert, S Dogniaux, F Vély… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Programmed Death-1 (PD-1), an inhibitory receptor expressed by activated lymphocytes, is
involved in regulating T-and B-cell responses. PD-1 and its ligands are exploited by a variety …
involved in regulating T-and B-cell responses. PD-1 and its ligands are exploited by a variety …
Efficacy of anti-TNF alpha in severe and/or refractory Behçet's disease: multicenter study of 124 patients
…, I Marie, L Perard, L Bouillet, F Cohen, D Sene… - Journal of …, 2015 - Elsevier
Objective To report the efficacy and safety of anti-TNF agents in patients with severe and/or
refractory manifestations of Behçet's disease (BD). Methods We performed a multicenter …
refractory manifestations of Behçet's disease (BD). Methods We performed a multicenter …
[HTML][HTML] Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome …
Objectives To analyze the clinical and immunological characteristics at enrollment in a large
prospective cohort of patients with primary Sjögren's syndrome (pSS) and to investigate the …
prospective cohort of patients with primary Sjögren's syndrome (pSS) and to investigate the …
Antiphospholipid antibodies, antiphospholipid syndrome and infections
D Sène, JC Piette, P Cacoub - Autoimmunity reviews, 2008 - Elsevier
Since the association between antiphospholipid antibodies (aPL) and syphilis was first
described, many other viral, bacterial and parasitic infections have been shown to induce …
described, many other viral, bacterial and parasitic infections have been shown to induce …