Complement and apoptosis

Z Fishelson, G Attali, D Mevorach - Molecular immunology, 2001 - Elsevier
… We did detect, however, DNA ladder formation in the same cells treated with actinomycin
D or cycloheximide, known activators of apoptosis. We concluded that sublytic MAC is not …

[HTML][HTML] Myocarditis after BNT162b2 mRNA vaccine against Covid-19 in Israel

D Mevorach, E Anis, N Cedar… - … England Journal of …, 2021 - Mass Medical Soc
Background Approximately 5.1 million Israelis had been fully immunized against coronavirus
disease 2019 (Covid-19) after receiving two doses of the BNT162b2 messenger RNA …

[HTML][HTML] Apoptotic cells induced signaling for immune homeostasis in macrophages and dendritic cells

U Trahtemberg, D Mevorach - Frontiers in immunology, 2017 - frontiersin.org
Mevorach D. The role of death-associated molecular patterns in the pathogenesis of
systemic lupus erythematosus. Rheum Dis Clin North Am (2004) 30(3):487–504, viii. …

Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness

S Beyth, Z Borovsky, D Mevorach, M Liebergall, Z Gazit… - Blood, 2005 - ashpublications.org
… The results shown in panels C and D are representative of 3 separate experiments. …
The results shown in panels C and D are representative of 3 separate experiments. …

Complement-dependent clearance of apoptotic cells by human macrophages

D Mevorach, JO Mascarenhas, D Gershov… - The Journal of …, 1998 - rupress.org
… Address correspondence to Dror Mevorach at his present address, The Laboratory for
Molecular and Cellular Immunology, Department of Medicine, Tel Aviv Sourasky Medical Center, …

[PDF][PDF] Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack

…, G Almogy, A Cuapio, E Hofer, D Mevorach… - Immunity, 2015 - cell.com
… nucleatum (Figure 3C), the killing of YTS ECO cells expressing TIGIT was inhibited (Figure
3D). This inhibition was less pronounced as compared to the PVR inhibition (Figure 3D). To …

Systemic exposure to irradiated apoptotic cells induces autoantibody production

D Mevorach, JL Zhou, X Song, KB Elkon - The Journal of experimental …, 1998 - rupress.org
During apoptotic cell death, cell surface ligands initiate phagocytosis of the dying cell.
Clearance of these apoptotic cells is thought to occur without an immune response. Since a …

Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus

…, A Porgador, A Honigman, B Plachter, D Mevorach… - Nature …, 2005 - nature.com
… We also determined the K D for the pp65 mAb. The antibody curve demonstrated a typical
antibody binding with a relatively slow K on rate of 1.99 × 10 4 and a very slow K off rate of …

Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a …

…, L Pank, T Savi, BG Alexandra, H Amital, D Mevorach… - The Lancet, 2017 - thelancet.com
Background Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid
arthritis. The Oral Rheumatoid Arthritis triaL (ORAL) Strategy aimed to assess the comparative …

[HTML][HTML] IL-1RA antibodies in myocarditis after SARS-CoV-2 vaccination

…, R Bals, M Krawczyk, D Mevorach… - … England Journal of …, 2022 - Mass Medical Soc
… In identical samples, isoelectric focusing of IL-1RA revealed a differentially charged IL-1RA
isoform (Panel D). Multiple Spearman’s correlation analyses were conducted of IL-1RA …