User profiles for D. Ligeiro
Dário LigeiroChampalimaud Foundation Verified email at ipst.min-saude.pt Cited by 1494 |
The HLA‐net GENE[RATE] pipeline for effective HLA data analysis and its application to 145 population samples from Europe and neighbouring areas
…, Z Grubic, T Jaatinen, L Kolesar, D Ligeiro… - Tissue …, 2014 - Wiley Online Library
In this review, we present for the first time an integrated version of the Gene[rate] computer
tools which have been developed during the last 5 years to analyse human leukocyte antigen …
tools which have been developed during the last 5 years to analyse human leukocyte antigen …
Strategies to work with HLA data in human populations for histocompatibility, clinical transplantation, epidemiology and population genetics: HLA‐NET methodological …
HLA‐NET (a European COST Action) aims at networking researchers working in bone
marrow transplantation, epidemiology and population genetics to improve the molecular …
marrow transplantation, epidemiology and population genetics to improve the molecular …
[HTML][HTML] Trained immunity for personalized cancer immunotherapy: current knowledge and future opportunities
…, M Castillo-Martin, A Beltrán, D Ligeiro… - Frontiers in …, 2020 - frontiersin.org
Memory formation, guided by microbial ligands, has been reported for innate immune cells.
Epigenetic imprinting plays an important role herein, involving histone modification after …
Epigenetic imprinting plays an important role herein, involving histone modification after …
Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population
FM Pimentel-Santos, D Ligeiro, M Matos, AF Mourão… - 2009 - comum.rcaap.pt
… between the marker and disease-associated variant of D’>0.8 and that the marker and
disease-… of 0.4%, minor allele frequencies of 0.1–0.5, and D’>0.8, the study had 80% power to …
disease-… of 0.4%, minor allele frequencies of 0.1–0.5, and D’>0.8, the study had 80% power to …
[HTML][HTML] Sialyl Tn-expressing bladder cancer cells induce a tolerogenic phenotype in innate and adaptive immune cells
…, JA Ferreira, F Calais, H Quinto, C Pen, D Ligeiro… - Molecular …, 2014 - Elsevier
Despite the wide acceptance that glycans are centrally implicated in immunity, exactly how
they contribute to the tilt immune response remains poorly defined. In this study, we sought to …
they contribute to the tilt immune response remains poorly defined. In this study, we sought to …
[HTML][HTML] ST3Gal. I sialyltransferase relevance in bladder cancer tissues and cell lines
Background The T antigen is a tumor-associated structure whose sialylated form (the sialyl-T
antigen) involves the altered expression of sialyltransferases and has been related with …
antigen) involves the altered expression of sialyltransferases and has been related with …
[HTML][HTML] Mortality in COVID-19 disease patients: Correlating the association of major histocompatibility complex (MHC) with severe acute respiratory syndrome 2 …
E de Sousa, D Ligeiro, JR Lérias, C Zhang… - International Journal of …, 2020 - Elsevier
Genetic factors such as the HLA type of patients may play a role in regard to disease severity
and clinical outcome of patients with COVID-19. Taking the data deposited in the GISAID …
and clinical outcome of patients with COVID-19. Taking the data deposited in the GISAID …
[HTML][HTML] Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive …
FM Pimentel-Santos, D Ligeiro, M Matos… - Arthritis research & …, 2011 - Springer
… However, an upregulation of C-type lectin domain family 4, member D (CLEC4D), another
gene involved in the innate immune response, was seen. CLEC4D has been found to be …
gene involved in the innate immune response, was seen. CLEC4D has been found to be …
Polymorphism at position–308 of the tumour necrosis factor α gene and rheumatoid arthritis pharmacogenetics
…, M Sobral, AF Mourao, J Cavaleiro, D Ligeiro… - Annals of the …, 2005 - ard.bmj.com
DISCUSSION A case of RP which followed 5 months of antiandrogen treatment with
another LH-RH analogue, goserelin (Zoladex) was reported a few years ago. 1 A hormonal …
another LH-RH analogue, goserelin (Zoladex) was reported a few years ago. 1 A hormonal …
IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity
…, R Branca, F Campilho, F Freitas, D Ligeiro… - Journal of Allergy and …, 2017 - jacionline.org
In a 2-stage, multicenter study involving 413 hematopoietic stem-cell transplantation (HSCT)
donor-recipient pairs, we confirmed that SNPs in IL10 are critical regulators of susceptibility …
donor-recipient pairs, we confirmed that SNPs in IL10 are critical regulators of susceptibility …