Depletion of regulatory T (T Reg ) cells in otherwise healthy individuals leads to multi-organ
autoimmune disease and inflammation. This indicates that in a normal immune system, …

Behçet’s disease, also known as the Silk Road Disease, is a rare systemic vasculitis disorder
of unknown etiology. Recurrent attacks of acute inflammation characterize Behçet’s disease…

Regulatory T (T reg ) cells suppress inflammation and regulate immune system activity. In
patients with systemic or organ-specific autoimmune diseases or those receiving transplanted …

Many viruses, including retroviruses, are characterized by their specific cell tropism 1–3 .
Lymphadenopathy-associated virus (LAV) is a human lymphotropic retrovirus isolated from …

The etiological agent of AIDS, LAV/HTLV-III, is common in Central Africa but is not endemic
in other areas of that continent. A novel human retrovirus, distinct from LAV/HTLV-III, has now …

… These particles are morphologically similar to D particles such as thosefound in Mason-Pfizer
virus or the virus recently isolated from simian AIDS (27, 28). However, no antigenic …

Background Patients with vasculitis induced by the hepatitis C virus (HCV) have reduced levels
of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of vasculitis …

CD4 + CD25 + immunoregulatory T cells play a pivotal role in preventing organ-specific
autoimmune diseases and in tolerance induction to allogeneic organ transplants. We …

Atherosclerosis is an immunoinflammatory disease elicited by accumulation of lipids in the
artery wall and leads to myocardial infarction and stroke 1 , 2 . Here, we show that naturally …

… ) twice a day for 11 d along with intraperitoneal administration of recombinant human IL-2
(Roussel Uclaf) or PBS at 10 5 IU/mouse, twice a day for the last 4 d. B16F10 or tumor variants …