User profiles for D. KURNIK
Daniel KurnikClinical Associate Professor, Rambam Health Care Campus and Technion, Israel Institute of … Verified email at rambam.health.gov.il Cited by 3538 |
Warfarin and vitamin K intake in the era of pharmacogenetics
Y Lurie, R Loebstein, D Kurnik… - British journal of …, 2010 - Wiley Online Library
The considerable variability in the warfarin dose–response relationship between individuals,
is explained mainly by genetic variation in its major metabolic (CYP2C9) and target (…
is explained mainly by genetic variation in its major metabolic (CYP2C9) and target (…
Complex drug-drug-disease interactions between amiodarone, warfarin, and the thyroid gland
D Kurnik, R Loebstein, Z Farfel, D Ezra, H Halkin… - Medicine, 2004 - journals.lww.com
… At 15 weeks, hypothyroidism was severe (see Table 1), and L-thyroxine supplements
were started at 50 μg/d and raised at 21 weeks to 86 μg/d. Thyroid hormone levels gradually …
were started at 50 μg/d and raised at 21 weeks to 86 μg/d. Thyroid hormone levels gradually …
Integration of genetic, clinical, and INR data to refine warfarin dosing
Well‐characterized genes that affect warfarin metabolism (cytochrome P450 (CYP) 2C9)
and sensitivity (vitamin K epoxide reductase complex 1 (VKORC1)) explain one‐third of the …
and sensitivity (vitamin K epoxide reductase complex 1 (VKORC1)) explain one‐third of the …
Combined genetic profiles of components and regulators of the vitamin K-dependent γ-carboxylation system affect individual sensitivity to warfarin
…, R Loebstein, S Almog, D Kurnik… - Thrombosis and …, 2006 - thieme-connect.com
We examined the influence of combined genotypes on interindividual variability in warfarin
dose-response. In 100 anticoagulated patients we quantified the effects of polymorphisms in: …
dose-response. In 100 anticoagulated patients we quantified the effects of polymorphisms in: …
[HTML][HTML] Analyzing medical research results based on synthetic data and their relation to real data results: systematic comparison from five observational studies
…, Y Lurie, ZS Azzam, J Khoury, D Kurnik… - JMIR medical …, 2020 - medinform.jmir.org
Background: Privacy restrictions limit access to protected patient-derived health information
for research purposes. Consequently, data anonymization is required to allow researchers …
for research purposes. Consequently, data anonymization is required to allow researchers …
The association of proton pump inhibitors and hypomagnesemia in the community setting
…, J Lomnicky, D Kurnik - The Journal of …, 2014 - Wiley Online Library
Evidence for the association between hypomagnesemia and proton pump inhibitors (PPIs),
highlighted by the 2011 FDA Drug Safety Communication, rests mainly on studies in …
highlighted by the 2011 FDA Drug Safety Communication, rests mainly on studies in …
Bioavailability of oral vs. subcutaneous low‐dose methotrexate in patients with Crohn's disease
D Kurnik, R Loebstein, E Fishbein… - Alimentary …, 2003 - Wiley Online Library
Background : Oral methotrexate and folic acid are partly absorbed by a common intestinal
transporter. Aim : To determine the relative bioavailability of oral low‐dose methotrexate …
transporter. Aim : To determine the relative bioavailability of oral low‐dose methotrexate …
[HTML][HTML] Choline transporter gene variation is associated with attention-deficit hyperactivity disorder
…, M Mazei-Robison, A Steele, DM Kurnik… - Journal of …, 2009 - Springer
The neurotransmitter acetylcholine (ACh) plays a critical role in brain circuits mediating motor
control, attention, learning and memory. Cholinergic dysfunction is associated with multiple …
control, attention, learning and memory. Cholinergic dysfunction is associated with multiple …
A genetic risk score that includes common type 2 diabetes risk variants is associated with gestational diabetes
…, D Kurnik, SP Collier, D Conway… - Clinical …, 2017 - Wiley Online Library
… in the general population, c GDM variants and d glycaemic trait variants in pregnant women
… (C1431T), that is in weak linkage disequilibrium with rs1801282 (D’=0.68, R 2 =.42) was …
… (C1431T), that is in weak linkage disequilibrium with rs1801282 (D’=0.68, R 2 =.42) was …
Prescriber response to computerized drug alerts for electronic prescriptions among hospitalized patients
… Author links open overlay panel Yael Zenziper Straichman a f , Daniel Kurnik a d , Ilan Matok
f , Hillel … Daniel Kurnik contributed to study design, data collection, statistical analysis, and …
f , Hillel … Daniel Kurnik contributed to study design, data collection, statistical analysis, and …