User profiles for D. Burkhardt

David Burkhardt

- Verified email at ucsf.edu - Cited by 2022

Daniel B Burkhardt

- Verified email at cellarity.com - Cited by 1598

Manifold learning-based methods for analyzing single-cell RNA-sequencing data

KR Moon, JS Stanley III, D Burkhardt, D van Dijk… - Current Opinion in …, 2018 - Elsevier
Recent advances in single-cell RNA sequencing technologies enable deep insights into
cellular development, gene regulation, and phenotypic diversity by measuring gene expression …

[HTML][HTML] Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources

GW Li, D Burkhardt, C Gross, JS Weissman - Cell, 2014 - cell.com
Quantitative views of cellular functions require precise measures of rates of biomolecule
production, especially proteins—the direct effectors of biological processes. Here, we present a …

Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

CB Little, A Barai, D Burkhardt, SM Smith… - … : Official Journal of …, 2009 - Wiley Online Library
… A–D, Maximal (A and B) and summed (C and D) scores for aggrecan loss in femoral and
tibial cartilage of wild-type and MMP-13–knockout mice 4 and 8 weeks after medial meniscal …

Cellular mechanisms of tumour suppression by the retinoblastoma gene

DL Burkhart, J Sage - Nature Reviews Cancer, 2008 - nature.com
The retinoblastoma (RB) tumour suppressor gene is functionally inactivated in a broad range
of paediatric and adult cancers, and a plethora of cellular functions and partners have been …

Visualizing structure and transitions in high-dimensional biological data

…, D Van Dijk, Z Wang, S Gigante, DB Burkhardt… - Nature …, 2019 - nature.com
The high-dimensional data created by high-throughput technologies require visualization
tools that reveal data structure and patterns in an intuitive form. We present PHATE, a …

Pulmonary vein isolation for the treatment of atrial fibrillation in patients with impaired systolic function

…, D Bash, R Schweikert, D Burkhardt… - Journal of the American …, 2004 - jacc.org
Objectives : We aimed to determine the safety and efficacy of pulmonary vein isolation (PVI)
in atrial fibrillation (AF) patients with impaired left ventricular (LV) systolic function. …

Endo-epicardial homogenization of the scar versus limited substrate ablation for the treatment of electrical storms in patients with ischemic cardiomyopathy

L Di Biase, P Santangeli, DJ Burkhardt, R Bai… - Journal of the American …, 2012 - jacc.org
Objectives : This study investigated the impact on recurrences of 2 different substrate
approaches for the treatment of these arrhythmias. Background : Catheter ablation of electrical …

The risk of thromboembolism and need for oral anticoagulation after successful atrial fibrillation ablation

…, R Horton, P Mohanty, D Patel, DJ Burkhardt… - Journal of the American …, 2010 - jacc.org
Burkhardt … Steven D., Rostock T., Lutomsky B.et al. : "What is the real atrial fibrillation burden
after … Burkhardt is a chief medical advisor for Stereotaxis. Dr. Haissaguerre has received …

[HTML][HTML] Topographical analysis of the structural, biochemical and dynamic biomechanical properties of cartilage in an ovine model of osteoarthritis

RC Appleyard, D Burkhardt, P Ghosh, R Read… - Osteoarthritis and …, 2003 - Elsevier
Objective The relationship between the topographical variations in the structural, biochemical
and dynamic biomechanical properties of articular cartilage (AC) before and 6 months …

Mitochondrial phylogenomics of Hemiptera reveals adaptive innovations driving the diversification of true bugs

…, EG Chapman, D Burkhardt… - … of the Royal …, 2017 - royalsocietypublishing.org
Hemiptera, the largest non-holometabolous order of insects, represents approximately 7%
of metazoan diversity. With extraordinary life histories and highly specialized morphological …