Background Granulomatous disease (GD) will develop in a subset of patients with common
variable immunodeficiency (CVID). Little is known about the efficacy of therapeutic agents …

Microsporidiosis first came to prominence as an opportunistic infection in patients with acquired
immunodeficiency syndrome. Microsporidia are now emerging pathogens responsible …

… (D) IL-6 was assessed in 5 patients at days −5 and +7, considering days 0 and +1 the
days of CPT. (F) ddPCR was assessed in 9 patients with a sensitivity threshold of 1.17 log (copies …

… AD, IgG (Fig 6, A), IgA (Fig 6, B), and IgM levels (Fig 6, C) and B-cell numbers (Fig 6, D) of
patients with APDS2 before onset of immunoglobulin replacement or other therapies. EH, CD4 …

… (D) SIgA-binding levels of ex vivo purified and fixed microbiota are measured by a flow
cytometry–based assay. Gray histograms represent isotype control, and black lines represent anti-…

Autosomal dominant deficiency of signal transducer and activator of transcription 3 (STAT3)
is the main genetic etiology of hyper-immunoglobulin (Ig) E syndrome. We documented the …

Introduction B-cell depletion with rituximab (RTX) is widely used to treat autoimmune diseases,
especially as second-line therapy for immune thrombocytopenia (ITP). The incidence of …

Life-threatening “breakthrough” cases of critical COVID-19 are attributed to poor or waning
antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting …

Background. Common variable immunodeficiency (CVID) is a primary immune deficiency
defined by defective antibody production. In most series, a small proportion of patients present …

… 2‐( 18 F)fluoro‐2‐deoxy‐D‐glucose positron emission tomography/computed tomography
was useful in 62 patients for staging/classification of the disease and for excluding associated …