Objective To develop new classification criteria for systemic lupus erythematosus ( SLE )
jointly supported by the European League Against Rheumatism ( EULAR ) and the American …

… DT Boumpas1 … Correspondence to Dr DT Boumpas, Departments of Internal Medicine
and Rheumatology, University of Crete School of Medicine, 71 003, 1 Voutes Street, Heraklion, …

… Boumpas: Although the cause and pathogenesis of many immunologically mediated
diseases are not completely understood, it is known that the localization of leukocytes at sites of …

Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …

Objectives To develop recommendations for the management of adult and paediatric lupus
nephritis (LN). Methods The available evidence was systematically reviewed using the …

Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable
presentations, course and prognosis. We sought to develop evidence-based recommendations …

Pulse cyclophosphamide is more effective than prednisone alone in preventing renal failure
in lupus nephritis. We undertook a randomised, controlled trial to find out whether pulse …

Objective CD40–CD40 ligand (CD40L) interactions play a significant role in the production
of autoantibodies and tissue injury in lupus nephritis. We performed an open‐label, multiple‐…

Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus
erythematosus (SLE). Although SLE is—by and large—a systemic disease, occasionally it …

Background: Uncertainty exists about the efficacy and toxicity of bolus therapy with
methylprednisolone or of the combination of methylprednisolone and cyclophosphamide in the …