Tendon xanthomatosis often accompanies familial hypercholesterolaemia, but it can also
occur in other pathologic states. Achilles tendons are the most common sites of tendon …

Adiponectin is secreted by the adipose tissue and it has been shown to be down‐regulated
in states of insulin resistance and in cardiovascular disease. It has also been found to be …

Randomized controlled trials with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitors (statins) have consistently demonstrated significant reductions in …

Background: Tumour necrosis factor α (TNFα) may be an important mediator of insulin
resistance. Infliximab is a chimeric monoclonal, high affinity antibody against the soluble and …

Background: Treatment with lipid‐lowering drugs decreases the risk of having a cardiovascular
event by 30% according to several large intervention trials. However, both in these trials …

Background: Visfatin [pre-B cell colony-enhancing factor (PBEF)] is a cytokine highly
expressed in visceral fat that exhibits insulin-mimetic properties. However, its role in insulin-…

What is known and objective: Rimonabant, a cannabinoid receptor blocker, has recently
been used in clinical practice for weight loss and weight maintenance. Our aim was to review …

Increased plasma visfatin levels in subjects with the metabolic syndrome. - Abstract - Europe
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Semaglutide is a glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) with a long elimination
half‐life, allowing subcutaneous (sc) administration once per week. Both the European …

Obesity is a pathological condition aggregating a substantial number of proatherogenic
factors, such as insulin resistance, type 2 diabetes mellitus, dyslipidaemia and hypertension. In …