User profiles for D. D. Patel
 | Dhavalkumar D PatelUCB Verified email at ucb.com Cited by 18685 |
Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of …
Human immunoglobulin prepared for intravenous administration (IGIV) has a number of
important uses in the treatment of disease. Some of these are in diseases for which acceptable …
important uses in the treatment of disease. Some of these are in diseases for which acceptable …
The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection
…, ML Markert, GD Sempowski, DD Patel… - Annual review of …, 2000 - annualreviews.org
The human thymus is a complex chimeric organ comprised of central (thymic epithelial
space) and peripheral (perivascular space) components that functions well into adult life to …
space) and peripheral (perivascular space) components that functions well into adult life to …
[PDF][PDF] Th17 cell pathway in human immunity: lessons from genetics and therapeutic interventions
DD Patel, VK Kuchroo - Immunity, 2015 - cell.com
The T helper 17 (Th17) cell pathway has been linked by genome-wide association studies
to multiple autoimmune diseases. Identification of the genetic causes of primary …
to multiple autoimmune diseases. Identification of the genetic causes of primary …
The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 …
…, M Pietropaolo, GS Eisenbarth, ST Bennett, DD Patel - Nature …, 1997 - nature.com
Type 1, or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease associated
with loss of tolerance to several pancreatic islet cell molecules, including insulin, glutamic …
with loss of tolerance to several pancreatic islet cell molecules, including insulin, glutamic …
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
W Hueber, DD Patel, T Dryja, AM Wright… - Science translational …, 2010 - science.org
Interleukin-17A (IL-17A) is elaborated by the T helper 17 (T H 17) subset of T H cells and
exhibits potent proinflammatory properties in animal models of autoimmunity, including collagen…
exhibits potent proinflammatory properties in animal models of autoimmunity, including collagen…
[PDF][PDF] A pathogenetic role for TNFα in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency
…, E Carballo, DM Lee, WS Lai, MJ Thompson, DD Patel… - Immunity, 1996 - cell.com
Tristetraprolin (TTP) is a widely expressed potential transcription factor that contains two
unusual CCCH zinc fingers and is encoded by the immediate–early response gene, Zfp-36. …
unusual CCCH zinc fingers and is encoded by the immediate–early response gene, Zfp-36. …
Fractalkine and CX3CR1 Mediate a Novel Mechanism of Leukocyte Capture, Firm Adhesion, and Activation under Physiologic Flow
Leukocyte migration into sites of inflammation involves multiple molecular interactions between
leukocytes and vascular endothelial cells, mediating sequential leukocyte capture, rolling…
leukocytes and vascular endothelial cells, mediating sequential leukocyte capture, rolling…
Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand.
MA Bowen, DD Patel, X Li, B Modrell… - The Journal of …, 1995 - rupress.org
Antibody-blocking studies have demonstrated the role of CD6 in thymocyte-thymic epithelial
(TE) cell adhesion. Here we report that CD6 expressed by COS cells mediates adhesion to …
(TE) cell adhesion. Here we report that CD6 expressed by COS cells mediates adhesion to …
CXCR3 and CCR5 ligands in rheumatoid arthritis synovium
DD Patel, JP Zachariah, LP Whichard - Clinical immunology, 2001 - Elsevier
The pathogenesis of rheumatoid arthritis (RA) may be mediated by Th1-type T cells. Since
chemokine receptors CXCR3 and CCR5 are preferentially expressed on Th1 cells, we tested …
chemokine receptors CXCR3 and CCR5 are preferentially expressed on Th1 cells, we tested …
Hematopoietic stem cell transplantation for severe combined immunodeficiency in the neonatal period leads to superior thymic output and improved survival
LA Myers, DD Patel, JM Puck… - Blood, The Journal of …, 2002 - ashpublications.org
All genetic types of severe combined immunodeficiency (SCID) can be cured by stem cell
transplantation from related donors. The survival rate approaches 80%, and most deaths result …
transplantation from related donors. The survival rate approaches 80%, and most deaths result …