… and tile Sharp method modified by van der Heijde, scored by … -trained readers, the van der
Heijde modification showed the … the Sharp method and the van der Heijde modification is the …

Background The value of intensive combination therapy in early rheumatoid arthritis is
unproven. In a multicentre, double-blind, randomised trial (COBRA), we compared the …

… in van der Heijde modification of the total Sharp score at week 54: 0.4 5.8 and 0.5 5.6 versus
3.7 9.6, respectively; P< 0.001 for each comparison). In addition, physical function improved …

… Two independent assessors scored radiographs in sequence according to the Sharp/van
der Heijde method. Outcomes were analyzed by generalized estimating equations on the …

… Radiographic joint damage was assessed using the modified Sharp/van der Heijde score
(SHS). The relationship between disease activity measures at baseline and week 14, as well …

The literature on prognostic features on the final outcome in RA is reviewed. It is generally
agreed that female sex and a positive RF are variables indicating a poor prognosis. Long-…

Objective To select the most appropriate radiologic scoring method for the evaluation of
radiographic progression in ankylosing spondylitis (AS) in clinical trials. Methods The validity of …

… Radiologic damage was measured by the Sharp/van der Heijde score in both cohorts. Data
were analyzed with longitudinal regression analysis (generalized estimating equations [GEE]…

In a prospective followup study of 147 patients with rheumatoid arthritis of recent onset, we
assessed the progression of radiographic evidence of joint damage on films of the patients' …

… week 54 in the van der Heijde modification of the … van der Waerden scores for radiographic
progression. This test converts the ranks to quantiles of the normal distribution, ie, the van der …