Adalimumab, a fully human anti–tumor necrosis factor α monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the …
…, LW Moreland, MH Weisman, CA Birbara… - Arthritis & …, 2003 - Wiley Online Library
Objective To evaluate the efficacy and safety of adalimumab (D2E7), a fully human monoclonal
tumor necrosis factor α antibody, in combination with methotrexate (MTX) in patients with …
tumor necrosis factor α antibody, in combination with methotrexate (MTX) in patients with …
[HTML][HTML] Abatacept for rheumatoid arthritis refractory to tumor necrosis factor α inhibition
…, Y Sherrer, J Kremer, C Birbara… - … England Journal of …, 2005 - Mass Medical Soc
Background A substantial number of patients with rheumatoid arthritis have an inadequate
or unsustained response to tumor necrosis factor α (TNF-α) inhibitors. We conducted a …
or unsustained response to tumor necrosis factor α (TNF-α) inhibitors. We conducted a …
Infliximab improves signs and symptoms of psoriatic arthritis: results of the IMPACT 2 trial
C Antoni, GG Krueger, K de Vlam, C Birbara… - Annals of the …, 2005 - ard.bmj.com
Objectives: To evaluate further in a phase III, double blind trial the efficacy of infliximab in
patients with active psoriatic arthritis (PsA), as observed in the smaller IMPACT trial. Methods: …
patients with active psoriatic arthritis (PsA), as observed in the smaller IMPACT trial. Methods: …
[HTML][HTML] Tanezumab for the treatment of pain from osteoarthritis of the knee
NE Lane, TJ Schnitzer, CA Birbara… - … England Journal of …, 2010 - Mass Medical Soc
Background Increased expression of nerve growth factor in injured or inflamed tissue is
associated with increased pain. This proof-of-concept study was designed to investigate the …
associated with increased pain. This proof-of-concept study was designed to investigate the …
Adalimumab, a fully human anti tumor necrosis factor-alpha monoclonal antibody, and concomitant standard antirheumatic therapy for the treatment of rheumatoid …
…, RM Fleischmann, V Strand, CA Birbara… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: This study, known as STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis),
evaluated the safety and efficacy of adalimumab (Humira), a fully human monoclonal …
evaluated the safety and efficacy of adalimumab (Humira), a fully human monoclonal …
Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3)
…, FJ Blanco, J Crowley, CA Birbara… - Annals of the …, 2016 - ard.bmj.com
Objective To evaluate apremilast treatment in patients with active psoriatic arthritis,
including current skin involvement, despite prior therapy with conventional disease-modifying …
including current skin involvement, despite prior therapy with conventional disease-modifying …
Immune responses following administration of influenza and pneumococcal vaccines to patients with rheumatoid arthritis receiving adalimumab.
JL Kaine, AJ Kivitz, C Birbara, AY Luo - The Journal of rheumatology, 2007 - jrheum.org
OBJECTIVE: This study compared the immunogenicity of influenza and pneumococcal
vaccines in adult patients with rheumatoid arthritis (RA) receiving adalimumab or placebo. …
vaccines in adult patients with rheumatoid arthritis (RA) receiving adalimumab or placebo. …
Efficacy and safety of tanezumab in the treatment of chronic low back pain
N Katz, DG Borenstein, C Birbara, C Bramson… - PAIN®, 2011 - Elsevier
Increased nerve growth factor levels are associated with chronic pain conditions, including
chronic low back pain (LBP). This study examined safety and analgesic efficacy of tanezumab…
chronic low back pain (LBP). This study examined safety and analgesic efficacy of tanezumab…
Infliximab maintains a high degree of clinical response in patients with active psoriatic arthritis through 1 year of treatment: results from the IMPACT 2 trial
…, K de Vlam, PP Geusens, C Birbara… - Annals of the …, 2007 - ard.bmj.com
Objective: To evaluate the efficacy and safety of infliximab through 1 year in patients with
psoriatic arthritis (PsA) enrolled in the IMPACT 2 trial. Methods: In this double blind, placebo …
psoriatic arthritis (PsA) enrolled in the IMPACT 2 trial. Methods: In this double blind, placebo …
[HTML][HTML] Treatment of chronic low back pain with etoricoxib, a new cyclo-oxygenase-2 selective inhibitor: improvement in pain and disability—a randomized, placebo …
CA Birbara, AD Puopolo, DR Munoz, EA Sheldon… - The journal of pain, 2003 - Elsevier
We evaluated etoricoxib, a novel COX-2–specific inhibitor, in 319 patients with chronic low
back pain (LBP) in this double-blind, placebo-controlled trial. Patients were randomized to a …
back pain (LBP) in this double-blind, placebo-controlled trial. Patients were randomized to a …