Influence of glucosamine sulphate on oxidative stress in human osteoarthritic chondrocytes: effects on HO-1, p22Phox and iNOS expression
C Valvason, E Musacchio, A Pozzuoli… - …, 2008 - academic.oup.com
Objective. Reactive oxygen species (ROS) are major determinants in the alteration of
articular cartilage. Among protective cellular mechanisms, the inducible isoform of haem …
articular cartilage. Among protective cellular mechanisms, the inducible isoform of haem …
Immune response against gene therapy vectors: influence of synovial fluid on adeno-associated virus mediated gene transfer to chondrocytes
V Cottard, C Valvason, G Falgarone, D Lutomski… - Journal of Clinical …, 2004 - Springer
… ◦ C prior to being transferred to the C20A4 cells. For the inhibitionreversing experiment, SF
and sera … ◦ C and for 4 h at 37 ◦ C, respectively, to eliminate all traces of sulfate ammonium. All …
and sera … ◦ C and for 4 h at 37 ◦ C, respectively, to eliminate all traces of sulfate ammonium. All …
Relationship between angiogenesis and inflammation in experimental arthritis
G Clavel, C Valvason, K Yamaoka, D Lemeiter… - European cytokine …, 2006 - jle.com
Background. Angiogenesis is involved in rheumatoid arthritis (RA) leading to leucocyte
recruitment and inflammation in the synovium. Furthermore, synovial inflammation itself further …
recruitment and inflammation in the synovium. Furthermore, synovial inflammation itself further …
The tumor necrosis factor-α-blocking agent infliximab inhibits interleukin 1ß (IL-1ß) and IL-6 gene expression in human osteoblastic cells
E Musacchio, C Valvason, C Botsios, F Ostuni… - The Journal of …, 2009 - jrheum.org
Objective. Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine involved in the
pathogenesis of several rheumatic diseases, including rheumatoid arthritis (RA), associated with …
pathogenesis of several rheumatic diseases, including rheumatoid arthritis (RA), associated with …
Laboratory investigations in osteoarthritis
L Punzi, F Oliviero, R Ramonda, C Valvason… - Aging clinical and …, 2003 - Springer
… as diagnostic “markers”, erythrocyte sedimentation rate (ESR) and C reactive protein (CRP)
are useful in the basic but essential … Increased urinary type II collagen C-telopeptide (CTX-II), …
are useful in the basic but essential … Increased urinary type II collagen C-telopeptide (CTX-II), …
Immunogenetic aspects of erosive osteoarthritis of the hand in patients from northern Italy
…, V Barbieri, A Piccoli, C Valvason… - Scandinavian journal …, 2011 - Taylor & Francis
… : pre-denaturation 2 min at 94C; denaturation 10 s at 94C; annealing and extension 60 s at
… C for 10 cycles; denaturation 10 s at 94C; annealing 50 s at 61C; and extension 30 s at 72C …
… C for 10 cycles; denaturation 10 s at 94C; annealing 50 s at 61C; and extension 30 s at 72C …
Synoviocyte infection with adeno-associated virus (AAV) is neutralized by human synovial fluid from arthritis patients and depends on AAV serotype
MC Boissier, D Lemeiter, C Clavel, C Valvason… - Human gene …, 2007 - liebertpub.com
Intraarticular gene transfer with adeno-associated viral (AAV) vectors may allow efficient
therapeutic transgene expression within the joint in diseases such as rheumatoid arthritis (RA), …
therapeutic transgene expression within the joint in diseases such as rheumatoid arthritis (RA), …
Frequency of the bleeding risk in patients receiving warfarin submitted to arthrocentesis of the knee
G Salvati, L Punzi, M Pianon, C Valvason, F Schiavon… - Reumatismo, 2003 - reumatismo.org
Objective: To evaluate the potential bleeding risks of arthrocentesis in patients with different
arthropathies and taking oral anticoagulants. Materials and methods: Fifteen consecutive …
arthropathies and taking oral anticoagulants. Materials and methods: Fifteen consecutive …
Further insights about the beneficial effects of n-3 fatty acids in the early molecular events of renal fibrosis in vitro.
G Priante, E Musacchio, C Valvason, G Clari… - Journal of …, 2012 - europepmc.org
Background Accumulating experimental and clinical evidence reveals beneficial effects of n-3
polyunsaturated fatty acids (PUFAs) in kidney disease by modulating inflammation and …
polyunsaturated fatty acids (PUFAs) in kidney disease by modulating inflammation and …
EPA and DHA suppress AngII-and arachidonic acid-induced expression of profibrotic genes in human mesangial cells.
G Priante, E Musacchio, C Valvason… - Journal of …, 2009 - europepmc.org
Background There is some evidence suggesting a close relationship between polyunsaturated
fatty acids (PUFAs) and renal inflammation and fibrosis, which are crucial stages in …
fatty acids (PUFAs) and renal inflammation and fibrosis, which are crucial stages in …