User profiles for C. Specker
Christof SpeckerProfessor Dr. med. (MD, PhD), Essen/Düsseldorf, Germany Verified email at hhu.de Cited by 6324 |
Pregnancy in systemic lupus erythematosus and antiphospholipid syndrome
R Fischer-Betz, C Specker - Best practice & research Clinical rheumatology, 2017 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with a
high prevalence in females of childbearing age. Pregnancy in SLE nowadays has favorable …
high prevalence in females of childbearing age. Pregnancy in SLE nowadays has favorable …
Current state of evidence on 'off-label'therapeutic options for systemic lupus erythematosus, including biological immunosuppressive agents, in Germany, Austria and …
…, H Schulze-Koops, JS Smolen, C Specker… - Lupus, 2012 - journals.sagepub.com
Systemic lupus erythematosus (SLE) can be a severe and potentially life-threatening
disease that often represents a therapeutic challenge because of its heterogeneous organ …
disease that often represents a therapeutic challenge because of its heterogeneous organ …
Serum Jo-1 autoantibody and isolated arthritis in the antisynthetase syndrome: review of the literature and report of the experience of AENEAS collaborative group
Anti-Jo-1 is the most frequently detectable antibody in the antisynthetase syndrome (ASSD),
an autoimmune disease characterized by the occurrence of arthritis, myositis, and interstitial …
an autoimmune disease characterized by the occurrence of arthritis, myositis, and interstitial …
[HTML][HTML] Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: results from the COVID-19 Global …
…, U Müller-Ladner, C Specker… - Annals of the …, 2021 - ard.bmj.com
Objective To investigate baseline use of biologic or targeted synthetic (b/ts) disease-modifying
antirheumatic drugs (DMARDs) and COVID-19 outcomes in rheumatoid arthritis (RA). …
antirheumatic drugs (DMARDs) and COVID-19 outcomes in rheumatoid arthritis (RA). …
[HTML][HTML] Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)
…, G Chehab, A Rubbert-Roth, C Specker… - Arthritis research & …, 2011 - Springer
Introduction Evidence from a number of open-label, uncontrolled studies has suggested that
rituximab may benefit patients with autoimmune diseases who are refractory to standard-of-…
rituximab may benefit patients with autoimmune diseases who are refractory to standard-of-…
[HTML][HTML] Clinical spectrum time course in anti Jo-1 positive antisynthetase syndrome: results from an international retrospective multicenter study
Anti Jo-1 antibodies are the main markers of the antisynthetase syndrome (ASSD), an
autoimmune disease clinically characterized by the occurrence of arthritis, myositis, and interstitial …
autoimmune disease clinically characterized by the occurrence of arthritis, myositis, and interstitial …
High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus
A Perniok, F Wedekind, M Herrmann, C Specker… - Lupus, 1998 - journals.sagepub.com
Increased in vitro apoptosis and altered expression of apoptosis-related molecules have
been reported in systemic lupus erythematosus (SLE). It was speculated that autoantigens …
been reported in systemic lupus erythematosus (SLE). It was speculated that autoantigens …
Older age, comorbidity, glucocorticoid use and disease activity are risk factors for COVID-19 hospitalisation in patients with inflammatory rheumatic and …
…, A Strangfeld, H Schulze-Koops, RE Voll, C Specker… - RMD open, 2021 - rmdopen.bmj.com
Introduction Whether patients with inflammatory rheumatic and musculoskeletal diseases (RMD)
are at higher risk to develop severe courses of COVID-19 has not been fully elucidated. …
are at higher risk to develop severe courses of COVID-19 has not been fully elucidated. …
[HTML][HTML] Influence of antisynthetase antibodies specificities on antisynthetase syndrome clinical spectrum time course
…, M Romano, F Bonella, C Specker… - Journal of clinical …, 2019 - mdpi.com
Antisynthetase syndrome (ASSD) is a rare clinical condition that is characterized by the
occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung …
occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung …
Characteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus: data from the COVID-19 Global Rheumatology Alliance
Aim To determine characteristics associated with more severe outcomes in a global registry
of people with systemic lupus erythematosus (SLE) and COVID-19. Methods People with …
of people with systemic lupus erythematosus (SLE) and COVID-19. Methods People with …