[HTML][HTML] A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with …

C Kedor, H Freitag, L Meyer-Arndt, K Wittke… - Nature …, 2022 - nature.com
A subset of patients has long-lasting symptoms after mild to moderate Coronavirus disease
2019 (COVID-19). In a prospective observational cohort study, we analyze clinical and …

[HTML][HTML] Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)

…, J Bellmann-Strobl, C Kedor, C Scheibenbogen… - Journal of Translational …, 2022 - Springer
… were performed under standardised conditions between 8:30 am and 12:30 pm after 15
min of supine rest in a quiet, dimly lit, air-conditioned room ensuring temperatures of 21–24 C. …

[HTML][HTML] Dysregulated autoantibodies targeting vaso-and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity

F Sotzny, IS Filgueiras, C Kedor, H Freitag… - Frontiers in …, 2022 - frontiersin.org
… The serum was purified and stored at −35C. IgG AAB against Angiotensin II receptor type
1/2 (AGTR1/2), ACE2, MAS1, Bradykinin receptor B1 (BDKRB1), EDNRA/B, ADRA1/2A, ADRB1…

Chronic COVID-19 Syndrome and Chronic Fatigue Syndrome (ME/CFS) following the first pandemic wave in Germany–a first analysis of a prospective observational …

C Kedor, H Freitag, L Meyer-Arndt, K Wittke, T Zoller… - MedRxiv, 2021 - medrxiv.org
Objective Characterization of the clinical features of patients with persistent symptoms after
mild to moderate COVID-19 infection and exploration of factors associated with the …

Update on the therapy of adult-onset Still's disease with a focus on IL-1-inhibition: a systematic review

C Kedor, S Tomaras, D Baeumer… - Therapeutic Advances …, 2021 - journals.sagepub.com
Introduction: The past decade has seen increasingly rapid advances in understanding the
pathogenic nature of adult-onset Still’s disease (AOSD) and its shared symptoms with the …

[HTML][HTML] Autoantibodies to vasoregulative G-protein-coupled receptors correlate with symptom severity, autonomic dysfunction and disability in myalgic …

…, F Sotzny, S Bauer, A Philippe, C Kedor… - Journal of Clinical …, 2021 - mdpi.com
… The serum was purified and stored at −35 C. The AAB were measured in serum samples …
Duplicate samples of a 1:100 serum dilution were incubated at 4 C for 2 h. After washing steps, …

[HTML][HTML] Long-term symptom severity and clinical biomarkers in post-COVID-19/chronic fatigue syndrome: results from a prospective observational cohort

F Legler, L Meyer-Arndt, L Mödl, C Kedor… - …, 2023 - thelancet.com
Background Post-COVID-19 syndrome (PCS) is characterised by a wide range of symptoms,
primarily fatigue and exertion intolerance. While disease courses in the early months post-…

[HTML][HTML] Hand grip strength and fatigability: correlation with clinical parameters and diagnostic suitability in ME/CFS

B Jäkel, C Kedor, P Grabowski, K Wittke, S Thiel… - Journal of translational …, 2021 - Springer
Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex
and debilitating disease accompanied by muscular fatigue and pain. A functional measure to …

Canakinumab for Treatment of Adult-Onset Still's Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): phase II, randomised, double-blind, placebo …

C Kedor, J Listing, J Zernicke, A Weiß… - Annals of the …, 2020 - ard.bmj.com
… By using ANCOVA, a significantly higher improvement in disease activity score 28 (using
erythrocyte sedimentation rate value) DAS28(ESR) and disease activity score 28 (using C-…

[HTML][HTML] Serum of post-COVID-19 syndrome patients with or without ME/CFS differentially affects endothelial cell function in vitro

L Flaskamp, C Roubal, S Uddin, F Sotzny, C Kedor… - Cells, 2022 - mdpi.com
… Louis, MO, USA) for 5 min at 4 C and subsequently washed thrice with … C before addition
of 0.5% (v/v) patient or control serum diluted in blocking buffer to the cells for another 1 h at 37 C