Objective. Vasculopathy is a key factor in the pathophysiology of systemic sclerosis (SSc)
and the main cause for Raynaud phenomenon (RP), digital ulcers (DU), and/or pulmonary …

… found to raise dabigatran C max by 175% and AUC and C min by 127%. … C max reductions
of 67% and 66%, respectively. After the 7 and 14-day washouts from rifampin, the AUC and C …

Background Vortioxetine is the first mixed serotonin agonist and antagonist antidepressant
approved in the US. We sought to evaluate all published and unpublished data available to …

Use of the gabapentinoids for pain continues to increase. In 2018, the US Food and Drug
Administration (FDA) strengthened the warnings for both gabapentin and pregabalin to …

Background Patients with systemic sclerosis (SSc) are endagered by tissue fibrosis and by
microvasculopathy, with the latter caused by endothelial cell expansion/proliferation. SSc-…

Background Hepatitis C virus (HCV) transmission is primarily driven by injection drug use,
and acute HCV infection rates are increased in rural communities with substantial barriers to …

Competency standards in pharmacy education and training have been formulated by different
organizations to focus on various stages in the development of students, residents, and …

BACKGROUND: Although direct-acting antivirals (DAA) have revolutionized the treatment of
chronic hepatitis C virus (HCV), many state Medicaid programs have limited coverage …

Purpose of Review Polypharmacy, the use of ≥ 5 medications, is common in people with
multiple sclerosis and is associated with negative outcomes. The use of multiple medications is …

Background Uninformed opioid prescribing by dentists has contributed to the current opioid
crisis. This report describes the development and implementation of an innovative, interactive…