In the past years, the research on angiogenesis was mostly directed to the definition of the
mechanisms able to modulate vascular growth. We now understand that in many pathological …

… of 10 min at 95 C, followed by 40 cycles of 15 s at 95 C and 60 s at 60 C. Preparations of …
C for 2 min; (94 C for 30 s; 54 C (Regions 1, 2 and 3) and 64 C (claudin-5 CDS) for 30 s; 72 C …

Endothelial cell–cell adherens junctions (AJs) supervise fundamental vascular functions,
such as the control of permeability and transmigration of circulating leukocytes, and the …

Cerebral cavernous malformation (CCM) is a vascular dysplasia, mainly localized within the
brain and affecting up to 0.5% of the human population. CCM lesions are formed by …

Endothelial adherens junctions maintain vascular integrity. Arteries and veins differ in their
permeability but whether organization and strength of their adherens junctions vary has not …

Objective. To describe 3 cases of scleritis associated with etanercept use for rheumatoid
arthritis (RA) and to review the literature related to inflammatory eye diseases associated with …

The Wnt/β-catenin pathway is evolutionary conserved signaling system that regulates cell
differentiation and organogenesis. We show that endothelial specific stabilization of Wnt/β-…

VE‐cadherin is an endothelial‐specific transmembrane protein concentrated at cell‐to‐cell
adherens junctions. Besides promoting cell adhesion and controlling vascular permeability, …

… C–E. Quantification of percentage of retinal area covered by vascular lesions (C), vascular
front density at the leading edge of the plexus (D), and average distance covered by the …

… For BrdU immunostaining, sections were treated with 2N HCl for 1 h at 37C and neutralized
with borate buffer, pH 8.5. Sections were incubated for 48 h at 4C in primary antibody diluted …