Our current knowledge of human biology is often based on studying a wide range of animal
species. In particular, for understanding human diseases, the development of adequate …

For 10,000 years pigs and humans have shared a close and complex relationship. From
domestication to modern breeding practices, humans have shaped the genomes of domestic …

We report here the genome sequence of an ancient human. Obtained from ∼4,000-year-old
permafrost-preserved hair, the genome represents a male individual from the first known …

Background The dissection of complex traits of economic importance to the pig industry
requires the availability of a significant number of genetic markers, such as single nucleotide …

We have previously shown that cells mutant for TOP3, a gene encoding a prokaryotic-like
type I topoisomerase in Saccharomyces cerevisiae, display a pleiotropic phenotype including …

… denaturation at 94C for 2 minutes followed by 25 cycles of 94C for 30 seconds, 56C for 30
seconds and 72C for 30 seconds, followed by a final extension of 8 minutes at 72C. Five µl of …

… We have shown that a His6 tag in the C terminus of Rad52 does not interfere with its … found
that oligo-C and oligo-D could not readily be annealed if mixed and incubated at 25C (Fig. 4B)…

Background Comparative whole genome analysis of Mammalia can benefit from the addition
of more species. The pig is an obvious choice due to its economic and medical importance …

The driving force behind the transition from a foraging to a farming lifestyle in prehistoric
Europe (Neolithization) has been debated for more than a century [1–3]. Of particular interest is …

Stature is affected by many polymorphisms of small effect in humans 1 . In contrast, variation
in dogs, even within breeds, has been suggested to be largely due to variants in a small …