Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

K Brandl, G Plitas, CN Mihu, C Ubeda, T Jia, M Fleisher… - Nature, 2008 - nature.com
Infection with antibiotic-resistant bacteria, such as vancomycin-resistant Enterococcus (VRE),
is a dangerous and costly complication of broad-spectrum antibiotic therapy 1 , 2 . How …

Incidence of fluoroquinolone-resistant and extended-spectrum β-lactamase-producing Escherichia coli at a comprehensive cancer center in the United States

Y Bhusal, CN Mihu, JJ Tarrand, KV Rolston - Chemotherapy, 2011 - karger.com
Background: Quinolones are used extensively for prophylaxis in high-risk cancer patients;
however, increasing quinolone resistance is being reported. Extended-spectrum β-lactamase (…

Does combination of lipid formulation of amphotericin B and echinocandins improve outcome of invasive aspergillosis in hematological malignancy patients?

CN Mihu, C Kassis, ER Ramos, Y Jiang, RY Hachem… - Cancer, 2010 - Wiley Online Library
BACKGROUND: In vitro and in vivo studies suggested that combination of lipid formulation
of amphotericin B (L‐AMB) and echinocandins may have a synergistic or additive effect …

Work‐up for infectious diarrhea after allogeneic hematopoietic stem cell transplantation: single specimen testing results in cost savings without compromising …

M Kamboj, CN Mihu, K Sepkowitz… - Transplant Infectious …, 2007 - Wiley Online Library
Background. Diarrhea is a common complication of allogeneic bone marrow transplantation.
Microbiologic stool studies are frequently ordered to rule out infectious etiology. The utility …

Rare case of septic arthritis caused by Candida krusei: case report and literature review

H Lu, MF Marengo, CN Mihu… - The Journal of …, 2012 - jrheum.org
We describe a 75-year-old white man with a diagnosis of acute myeloid leukemia (AML)
who was admitted to the University of Texas MD Anderson Cancer Center with neutropenic …

Risk factors and attributable mortality of late aspergillosis after T‐cell depleted hematopoietic stem cell transplantation

CN Mihu, E King, O Yossepovitch… - Transplant Infectious …, 2008 - Wiley Online Library
Aim. Invasive aspergillosis occurs in 5–15% of allogeneic hematopoietic stem cell transplant
(HSCT) recipients. Through the 1990s there has been an increase in the incidence of late …

[HTML][HTML] Risk factors for late Staphylococcus aureus bacteremia after allogeneic hematopoietic stem cell transplantation: a single-institution, nested case-controlled …

CN Mihu, J Schaub, S Kesh, A Jakubowski… - Biology of Blood and …, 2008 - Elsevier
We report on the incidence, risk factors, and outcome of late Staphylococcus aureus bacteremia
(SAB) in a cohort of 709 adult and pediatric patients at Memorial Sloan-Kettering Cancer …

Escherichia coli resistance to quinolones at a comprehensive cancer center

CN Mihu, PR Rhomberg, RN Jones, E Coyle… - … and infectious disease, 2010 - Elsevier
OBJECTIVE: As part of Meropenem Yearly Susceptibility Test Information Collection/USA
Surveillance Programme, we monitored the occurrence of quinolone resistance in Escherichia …

Infections in non-myeloablative hematopoietic stem cell transplantation patients with lymphoid malignancies: spectrum of infections, predictors of outcome and …

A Safdar, GH Rodriguez, CN Mihu… - Bone marrow …, 2010 - nature.com
The overall risk of infections is lower in patients undergoing non-myeloablative allogeneic
stem cell transplantation (NST) than in conventional stem cell transplant recipients. We sought …

[HTML][HTML] Hematologic safety profile of linezolid in the early periengraftment period after allogeneic stem cell transplantation

N Cohen, CN Mihu, SK Seo, D Chung, J Chou… - Biology of Blood and …, 2009 - Elsevier
Vancomycin-resistant enterococci (VRE) are common pathogens of bloodstream infections
in the peritransplantation period. Linezolid is approved by the FDA for treating VRE infections…