Why blockade of the renin–angiotensin system reduces the incidence of new-onset diabetes
Recent trials have suggested that inhibitors of the renin–angiotensin system (RAS), such as
angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs)…
angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs)…
Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials
Complex relationships exist between the gut microflora and their human hosts. Emerging
evidence suggests that bacterial dysbiosis within the colon may be involved in the …
evidence suggests that bacterial dysbiosis within the colon may be involved in the …
Incidence of chronic kidney disease among people with diabetes: a systematic review of observational studies
Aims The aim was to systematically review published articles that reported the incidence of
chronic kidney disease among people with diabetes. Methods A systematic literature search …
chronic kidney disease among people with diabetes. Methods A systematic literature search …
[HTML][HTML] A comparison of outcomes with angiotensin-converting–enzyme inhibitors and diuretics for hypertension in the elderly
Background Treatment of hypertension with diuretics, beta-blockers, or both leads to improved
outcomes. It has been postulated that agents that inhibit the renin–angiotensin system …
outcomes. It has been postulated that agents that inhibit the renin–angiotensin system …
[HTML][HTML] Effect of aspirin on cardiovascular events and bleeding in the healthy elderly
Background Aspirin is a well-established therapy for the secondary prevention of cardiovascular
events. However, its role in the primary prevention of cardiovascular disease is unclear, …
events. However, its role in the primary prevention of cardiovascular disease is unclear, …
[HTML][HTML] Cholesterol lowering in intermediate-risk persons without cardiovascular disease
Background Previous trials have shown that the use of statins to lower cholesterol reduces
the risk of cardiovascular events among persons without cardiovascular disease. Those trials …
the risk of cardiovascular events among persons without cardiovascular disease. Those trials …
Pet ownership and risk factors for cardiovascular disease
WP Anderson, CM Reid… - Medical journal of …, 1992 - Wiley Online Library
Objective: To compare risk factors for cardiovascular disease in pet owners and non‐owners.
Design and patients: Accepted risk factors for cardiovascular disease were measured in …
Design and patients: Accepted risk factors for cardiovascular disease were measured in …
[HTML][HTML] Blood-pressure lowering in intermediate-risk persons without cardiovascular disease
Background Antihypertensive therapy reduces the risk of cardiovascular events among high-risk
persons and among those with a systolic blood pressure of 160 mm Hg or higher, but its …
persons and among those with a systolic blood pressure of 160 mm Hg or higher, but its …
[HTML][HTML] Effect of aspirin on all-cause mortality in the healthy elderly
Background In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE)
trial, now published in the Journal, we report that the daily use of aspirin did not provide a …
trial, now published in the Journal, we report that the daily use of aspirin did not provide a …
2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: the ADAPT trial
Objectives : The purpose of this study was to determine whether a new accelerated diagnostic
protocol (ADP) for possible cardiac chest pain could identify low-risk patients suitable for …
protocol (ADP) for possible cardiac chest pain could identify low-risk patients suitable for …