A self-splicing RNA excises an intron lariat

CL Peebles, PS Perlman, KL Mecklenburg, ML Petrillo… - Cell, 1986 - cell.com
We have investigated the in vitro self-splicing of a class II mitochondrial intron. A model pre-mRNA
containing intron 5y of the oxi 3 gene of yeast mftochondrial DNA undergoes an …

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

A Sugino, CL Peebles, KN Kreuzer… - Proceedings of the …, 1977 - National Acad Sciences
A target protein for nalidixic and oxolinic acids in Escherichia coli, the nalA gene product (Pnal),
was purified to homogeneity as judged by gel electrophoresis, using an in vitro …

Energy coupling in DNA gyrase and the mechanism of action of novobiocin

…, NP Higgins, PO Brown, CL Peebles… - Proceedings of the …, 1978 - National Acad Sciences
Escherichia coli DNA gyrase catalyzes negative supercoiling of closed duplex DNA at the
expense of ATP. Two additional activities of the enzyme that have illuminated the energy …

Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin.

LE Andrade, EK Chan, I Raska, CL Peebles… - The Journal of …, 1991 - rupress.org
Antibodies producing an unusual immunofluorescent pattern were identified in the sera of
patients with diverse autoimmune features. This pattern was characterized by the presence of …

Mechanism of action of a yeast RNA ligase in tRNA splicing

CL Greer, CL Peebles, P Gegenheimer, J Abelson - Cell, 1983 - cell.com
… Products were analyzed by gel electrophoresis as described by Peebles et al. (I 983). … ) in
high-salt buffer as described by Peebles et al. (1983). was centrifuged at 200,000 xg for 2 hr. …

Comparative genomic analysis of 60 mycobacteriophage genomes: genome clustering, gene acquisition, and gene size

…, H Donis-Keller, MW Bogel, CL Peebles… - Journal of molecular …, 2010 - Elsevier
Mycobacteriophages are viruses that infect mycobacterial hosts. Expansion of a collection
of sequenced phage genomes to a total of 60—all infecting a common bacterial host—…

[HTML][HTML] Exploring the mycobacteriophage metaproteome: phage genomics as an educational platform

…, AL Smith, GM Zdanowicz, V Kumar, CL Peebles… - PLoS …, 2006 - journals.plos.org
Bacteriophages are the most abundant forms of life in the biosphere and carry genomes
characterized by high genetic diversity and mosaic architectures. The complete sequences of …

Arc regulates spine morphology and maintains network stability in vivo

CL Peebles, J Yoo, MT Thwin… - Proceedings of the …, 2010 - National Acad Sciences
Long-term memory relies on modulation of synaptic connections in response to experience.
This plasticity involves trafficking of AMPA receptors (AMPAR) and alteration of spine …

Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activity

NP Higgins, CL Peebles, A Sugino… - Proceedings of the …, 1978 - National Acad Sciences
Extensively purified DNA gyrase from Escherichia coli is inhibited by nalidixic acid and by
novobiocin. The enzyme is composed of two subunits, A and B, which were purified as …

Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease

CL Peebles, P Gegenheimer, J Abelson - Cell, 1983 - cell.com
… are numbered according to the scheme of Peebles et al. (… maintained and grown as
described by Peebles et al. (1979). … were prepared as described by Peebles et al. (1979) using …