[HTML][HTML] Clinical outcomes and biologic costs of switching between tumor necrosis factor inhibitors in US veterans with rheumatoid arthritis

GW Cannon, SL DuVall, CL Haroldsen, L Caplan… - Advances in …, 2016 - Springer
… Cannon GW, DuVall SL, Hayden CL, et al. Persistence and dose escalation of tumor …
CL Haroldsen has nothing to disclose. L. Caplan was supported by VA grant CDA 07-221 at …

Persistence and dose escalation of tumor necrosis factor inhibitors in US veterans with rheumatoid arthritis

GW Cannon, SL DuVall, CL Haroldsen… - The Journal of …, 2014 - jrheum.org
Objective. Limited evidence exists comparing the persistence, effectiveness, and costs of
biologic therapies for rheumatoid arthritis in clinical practice. Comparative effectiveness studies …

Neighborhood Deprivation, Race and Ethnicity, and Prostate Cancer Outcomes Across California Health Care Systems

…, C Roscoe, EA Duran, L Kwan, CL Haroldsen… - JAMA Network …, 2024 - jamanetwork.com
Importance Non-Hispanic Black (hereafter, Black) individuals experience worse prostate
cancer outcomes due to socioeconomic and racial inequities of access to care. Few studies …

PD29-04 ASSOCIATION OF AGENT ORANGE EXPOSURE AND PROSTATE CANCER INCIDENCE AND METASTASIS AMONG VIETNAM VETERANS DIAGNOSED …

…, AV Nguyen, L Kwan, CL Haroldsen… - The Journal of …, 2024 - auajournals.org
INTRODUCTION AND OBJECTIVE: Agent Orange, a dioxin-containing herbicide used
during the Vietnam War from 1962–1971, is a known carcinogen and presumptive causative …

MP68-19 CHARACTERISTICS AND OUTCOMES OF PRIMARY NEUROENDOCRINE/SMALL CELL PROSTATE CANCER OCCURRING IN THE VETERAN AFFAIRS …

…, AMY Green-Lott, L Kwan, CL Haroldsen… - The Journal of …, 2024 - auajournals.org
INTRODUCTION AND OBJECTIVE: Primary neuroendocrine/small cell prostate carcinoma (NEPC)
is extremely rare, but highly lethal. Understanding the molecular and biological …

[HTML][HTML] Mobility of transgenic nucleic acids and proteins within grafted rootstocks for agricultural improvement

VM Haroldsen, MW Szczerba, H Aktas… - Frontiers in Plant …, 2012 - frontiersin.org
Grafting has been used in agriculture for over 2000 years. Disease resistance and
environmental tolerance are highly beneficial traits that can be provided through use of grafting, …

Constitutively expressed DHAR and MDHAR influence fruit, but not foliar ascorbate levels in tomato

VM Haroldsen, CL Chi-Ham, S Kulkarni… - Plant Physiology and …, 2011 - Elsevier
Vitamin C (l-ascorbate, AsA) is an essential nutrient required in key metabolic functions in
humans and must be obtained from the diet, mainly from fruits and vegetables. Given its …

[HTML][HTML] Acetylator status impacts amifampridine phosphate (Firdapse™) pharmacokinetics and exposure to a greater extent than renal function

PE Haroldsen, Z Sisic, J Datt, DG Musson… - Clinical Therapeutics, 2017 - Elsevier
… The CL/F and CL R of amifampridine were decreased (2-fold and 6-fold lower, respectively)
… In this study, <20% of the amifampridine CL/F was represented by CL R in individuals with …

Genetic variation in aryl N‐acetyltransferase results in significant differences in the pharmacokinetic and safety profiles of amifampridine (3,4‐diaminopyridine) …

PE Haroldsen, MR Garovoy, DG Musson… - Pharmacology …, 2015 - Wiley Online Library
The clinical use of amifampridine phosphate for neuromuscular junction disorders is increasing.
The metabolism of amifampridine occurs via polymorphic aryl N‐acetyltransferase ( NAT …

Transgene mobilization and regulatory uncertainty for non-GE fruit products of transgenic rootstocks

VM Haroldsen, CL Chi-Ham, AB Bennett - Journal of biotechnology, 2012 - Elsevier
Genetically engineered (GE) rootstocks may offer some advantages for biotechnology
applications especially in woody perennial crops such as grape or walnut. Transgrafting combines …