The lipid A domain of lipopolysaccharide (LPS) is a unique, glucosamine‐based phospholipid
that makes up the outer monolayer of the outer membrane of most gram‐negative bacteria…

Chemotherapy remains the only practicable tool to control falciparum malaria in sub-Saharan
Africa, where >90% of the world's burden of malaria mortality and morbidity occurs. …

Molecular markers for drug resistant malaria represent public health tools of great but mostly
unrealized potential value. A key reason for the failure of molecular resistance markers to …

Anyone who has cultured Plasmodium falciparum~ s aware that confusion about the identity
of commonly used strains, and inadvertent contamination of one strain with another have …

Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the
artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum …

The antifolate combination of pyrimethamine (PM) and sulfadoxine (SD) is the last affordable
drug combination available for wide-scale treatment of falciparum malaria in Africa. …

Objective Blocking interleukin‐1 with anakinra in patients with the autoinflammatory syndrome
neonatal‐onset multisystem inflammatory disease (NOMID) reduces systemic and organ‐…

Background Resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine threatens
the antimalarial effectiveness of intermittent preventive treatment during pregnancy (IPTp) in …

Background Chloroquine remains the mainstay of treatment for Plasmodium vivax malaria
despite increasing reports of treatment failure. We did a systematic review and meta-analysis …

Following a decade-long scale up of malaria control through vector control interventions, the
introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination …