Aims Premature cardiovascular events complicate chronic inflammatory conditions. Low-dose
weekly methotrexate (MTX), the most widely used disease-modifying drug for rheumatoid …

Aims Vascular injury leading to endothelial dysfunction is a characteristic feature of chronic
renal disease, diabetes mellitus, and systemic inflammatory conditions, and predisposes to …

Although concern remains about the athero-thrombotic risk posed by cyclo-oxygenase (COX)-2-selective
inhibitors, recent data implicates rofecoxib, while celecoxib appears equivalent …

Historically, pregnancy has been considered to have a beneficial effect upon inflammatory
arthritis, with around 75% of women with rheumatoid arthritis (RA) reportedly improving. …

Considerable evidence indicates that serotonergic mechanisms, particularly the serotonin
transporter (5HTT), may mediate central effects of cocaine and may also be involved in …

SIR, Randomized controlled trials have not demonstrated a clear benefit of rituximab in
refractory SLE, likely due to study design problems [1, 2]. However, numerous other studies have …

In this study, a mixed group of 60 substance-dependent patients were randomly assigned to
12 weeks of treatment in either a high-structure, behaviorally oriented (HSB) or a low-…

Angiogenesis is an essential physiological process and an important factor in disease
pathogenesis. However, its exploitation as a clinical target has achieved limited success and …

We investigated whether pretreatment characteristics and measures of outcome differed for
alcohol-, cocaine-, and multisubstance-dependent patients receiving outpatient substance …

In this study, we aimed to examine the diagnostic yield of pericardial fluid biochemistry and
cytology and their prognostic significance in patients with percutaneously drained pericardial …