The coincidence between infections with parasitic worms and the reduced prevalence of
allergic disease in humans and in animal models has prompted the search for helminth …

Background & Aims We performed a multicenter study to determine whether transabdominal
bowel wall ultrasonography, a noninvasive procedure that does not require radiation, can …

Psoriasis is a common chronic inflammatory disease with characteristic skin alterations and
functions as a model of immune-mediated disorders. Cytokines have a key role in psoriasis …

Galectins have recently emerged as central regulators of the immune system. We have
previously demonstrated that carbohydrate-dependent binding of galectin-2 induces apoptosis in …

The objective of this study was to use data from a noninterventional study to evaluate the
effectiveness of adalimumab in rheumatoid arthritis (RA) patients during routine clinical practice …

Intestinal T lymphocytes activated by antigen are suspected to play a key role in enterogenic
spondyloarthropathies (SpA). Therefore, we aimed to identify and functionally characterize T…

Experimental colitis in mice is characterized by infiltration of activated T helper (Th) cells
and macrophages into the lamina propria. Particularly, these cells expressed CD44 variant …

Objective. To examine the influence of concomitant methotrexate (MTX) with adalimumab (ADA)
on outcomes in patients with psoriatic arthritis (PsA) using data from an observational …

Increased expression of CD44 variant isoforms have been shown on the inflammatory
infiltrates in human and mouse colitis and blockade or deletion of CD44 isoforms inhibit …

A major problem in inflammatory bowel disease (IBD) is the accumulation of highly activated
T-helper cells that are refractory to apoptosis induction. Hence, persistent inflammatory …