Anti‐tumor necrosis factor‐alpha therapy improves endothelial function and arterial stiffness in patients with moderate to severe psoriasis: a 6‐month prospective …

…, I Gómez‐Acebo, B Ubilla… - The Journal of …, 2016 - Wiley Online Library
The aim of the present study was to determine if the use of the anti‐tumor necrosis factor (
TNF )‐α monoclonal antibody adalimumab could improve endothelial function and arterial …

[HTML][HTML] A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis

…, N Ortego-Centeno, J Llorca, B Ubilla… - Scientific reports, 2017 - nature.com
The genetic component of Immunoglobulin-A (IgA) vasculitis is still far to be elucidated. To
increase the current knowledge on the genetic component of this vasculitis we performed the …

[HTML][HTML] Association of HLA-B* 41: 02 with Henoch-Schönlein Purpura (IgA Vasculitis) in Spanish individuals irrespective of the HLA-DRB1 status

…, N Ortego-Centeno, J Llorca, B Ubilla… - Arthritis research & …, 2015 - Springer
Introduction A study was conducted to determine whether the human leukocyte antigen (HLA)
B alleles are implicated in the susceptibility to Henoch-Schönlein purpura (HSP) in the …

[HTML][HTML] Expression of osteoprotegerin and its ligands, RANKL and TRAIL, in rheumatoid arthritis

…, F Genre, R López-Mejías, B Ubilla… - Scientific reports, 2016 - nature.com
Osteoprotegerin (OPG), receptor activator of nuclear factor-ΚB ligand (RANKL) and tumor
necrosis factor-related apoptosis-inducing ligand (TRAIL) have been involved in rheumatoid …

[HTML][HTML] Adipokines, biomarkers of endothelial activation, and metabolic syndrome in patients with ankylosing spondylitis

…, R López-Mejías, JA Miranda-Filloy, B Ubilla… - BioMed research …, 2014 - hindawi.com
Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease associated with
accelerated atherosclerosis and increased risk of cardiovascular (CV) disease. AS patients also …

Osteoprotegerin concentrations relate independently to established cardiovascular disease in rheumatoid arthritis

R López-Mejias, B Ubilla, F Genre, A Corrales… - The Journal of …, 2015 - jrheum.org
Objective. We determined whether osteoprotegerin (OPG) concentrations are associated with
established cardiovascular disease (CVD) among patients with rheumatoid arthritis (RA). …

[HTML][HTML] Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in …

…, JJ Alegre-Sancho, E Raya, V Mijares, B Ubilla… - Scientific reports, 2016 - nature.com
Association between elevated C-reactive protein (CRP) serum levels and subclinical
atherosclerosis and cardiovascular (CV) events was described in rheumatoid arthritis (RA). CRP, …

[HTML][HTML] Protective Role of the Interleukin 33 rs3939286 Gene Polymorphism in the Development of Subclinical Atherosclerosis in Rheumatoid Arthritis Patients

…, J Llorca, A Corrales, C González-Juanatey, B Ubilla… - PLOS …, 2015 - journals.plos.org
Objectives To determine whether the interleukin-33 (IL-33)-interleukin-1 receptor like 1 (IL-1RL1)
signaling pathway is implicated in the risk of subclinical atherosclerosis in patients with …

[PDF][PDF] Proprotein convertase subtilisin/kexin type 9 in rheumatoid arthritis

I Ferraz-Amaro, R López-Mejías, B Ubilla… - Clin Exp …, 2016 - clinexprheumatol.org
Objective Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that
regulates cholesterol metabolism through low-density lipoprotein receptor degradation and that …

[PDF][PDF] Interleukin 1 beta (IL1ß) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schönlein purpura

…, J Llorca, N Ortego-Centeno, B Ubilla… - Clin Exp …, 2016 - clinexprheumatol.org
Objective. Data from a small series suggested that the Interleukin 1 beta (IL1ß) rs16944
polymorphism may be associated with severe renal involvement and persistent renal damage (…