Involvement of NK cells and NKp30 pathway in antisynthetase syndrome
B Hervier, M Perez, Y Allenbach… - The Journal of …, 2016 - journals.aai.org
Antisynthetase syndrome (aSS) is characterized by the association of interstitial lung disease
and myositis with anti–tRNA synthetase autoantibodies. Immune mechanisms leading to …
and myositis with anti–tRNA synthetase autoantibodies. Immune mechanisms leading to …
High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses
…, Z Hélias-Rodzewicz, B Hervier… - Blood, The Journal …, 2012 - ashpublications.org
Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis.
BRAF mutations have been observed in Langerhans cell histiocytosis (LCH). We investigated …
BRAF mutations have been observed in Langerhans cell histiocytosis (LCH). We investigated …
Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E …
…, F Charlotte, P Cluzel, A Drier, B Hervier… - Blood, The Journal …, 2013 - ashpublications.org
Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis.
BRAF V600E gain-of-function mutations have been observed in 57% of cases of Langerhans …
BRAF V600E gain-of-function mutations have been observed in 57% of cases of Langerhans …
CNS involvement and treatment with interferon-α are independent prognostic factors in Erdheim-Chester disease: a multicenter survival analysis of 53 patients
L Arnaud, B Hervier, A Néel… - Blood, The Journal …, 2011 - ashpublications.org
Erdheim-Chester disease (ECD) is a rare form of non-Langerhans histiocytosis, with
noncodified therapeutic management and high mortality. No treatment has yet been shown to …
noncodified therapeutic management and high mortality. No treatment has yet been shown to …
224th ENMC International Workshop:: Clinico-sero-pathological classification of immune-mediated necrotizing myopathies Zandvoort, The Netherlands, 14–16 …
…, I de Groot, M de Visser, H Goebel, B Hervier… - Neuromuscular …, 2018 - Elsevier
Among the idiopathic inflammatory myopathies (IIMs), immune-mediated necrotizing myopathies
(IMNMs) have been identified as important and separate entities during the past years. …
(IMNMs) have been identified as important and separate entities during the past years. …
CMV drives clonal expansion of NKG2C+ NK cells expressing self‐specific KIRs in chronic hepatitis patients
…, P Bedossa, A Boudifa, B Hervier… - European journal of …, 2012 - Wiley Online Library
Natural killer (NK) cells are affected by infection with human cytomegalovirus (HCMV)
manifested by increased expression of the HLA‐E binding activating receptor NKG2C. We here …
manifested by increased expression of the HLA‐E binding activating receptor NKG2C. We here …
Hierarchical cluster and survival analyses of antisynthetase syndrome: phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity
B Hervier, H Devilliers, R Stanciu, A Meyer… - Autoimmunity …, 2012 - Elsevier
The clinical phenotype and evolution of antisynthetase syndrome (ASS) are heterogeneous.
This study was therefore undertaken to identify subgroups of ASS patients with similar …
This study was therefore undertaken to identify subgroups of ASS patients with similar …
Immune checkpoint inhibitor-related myositis and myocarditis in patients with cancer
…, S Knauss, O Ben Hadj Salem, B Hervier… - Neurology, 2018 - AAN Enterprises
Objective To report the clinicopathologic features and outcome of myositis in patients treated
with immune checkpoint inhibitors (ICIs) (irMyositis). Methods We retrospectively analyzed …
with immune checkpoint inhibitors (ICIs) (irMyositis). Methods We retrospectively analyzed …
[PDF][PDF] Reproducible and sustained efficacy of targeted therapy with vemurafenib in patients with BRAF (V600E)-mutated Erdheim-Chester disease
…, F Lifermann, A Idbaih, B Granel, B Graffin, B Hervier… - J Clin Oncol, 2015 - academia.edu
Purpose Histiocytoses are rare disorders with heterogeneous prognosis. BRAFV600E mutations
have been observed in half of patients with Langerhans cell histiocytosis (LCH) and in …
have been observed in half of patients with Langerhans cell histiocytosis (LCH) and in …
High risk of cancer in autoimmune necrotizing myopathies: usefulness of myositis specific antibody
…, A Bouvier, V Jooste, N Champtiaux, B Hervier… - Brain, 2016 - academic.oup.com
Cancer can occur in patients with inflammatory myopathies. This association is mainly
observed in dermatomyositis, and myositis-specific antibodies have allowed us to delineate …
observed in dermatomyositis, and myositis-specific antibodies have allowed us to delineate …