Objective To determine the efficacy, safety, and tolerability of 3 different dosages of CP‐690,550,
a potent, orally active JAK inhibitor, in patients with active rheumatoid arthritis (RA) in …

Background & Aims: The safety of selective cyclooxygenase-2 inhibitors in patients with
ulcerative colitis in remission is unknown. Methods: We performed a placebo-controlled pilot trial …

Objective. To evaluate efficacy and safety of CE-224,535, a selective P2X 7 receptor
antagonist, versus placebo, in patients with active rheumatoid arthritis (RA) and inadequate …

BACKGROUND: The For Angioedema Subcutaneous Treatment (FAST)-3 study was a phase
III, randomized, double-blind, placebo-controlled study of icatibant (bradykinin B 2 receptor …

OBJECTIVE: To determine what sleep abnormalities may exist in children with juvenile
rheumatoid arthritis (JRA). and their relationship to pain, dysfunction. and disease activity. …

A polymerase chain reaction (PCR) assay that detects Borrelia burgdorferi DNA in
cerebrospinal fluid (CSF) was evaluated as a diagnostic test for acute or chronic Lyme …

Objectives: To determine the efficacy of CP-690,550 in improving pain, function and health
status in patients with moderate to severe active rheumatoid arthritis (RA) and an inadequate …

Objective This phase 3 study was undertaken to investigate the efficacy and safety of
lenabasum, a cannabinoid type 2 receptor agonist, in patients with diffuse cutaneous systemic …

Objective To determine whether Borrelia burgdorferi DNA may be detected in synovial tissue
from patients with Lyme arthritis who have persistent synovial inflammation after antibiotic …

Background. In adults a subtle encephalopathy characterized primarily by memory impairment,
irritability and somnolence may occur months to years after classic manifestations of …