The clinical phenotype and evolution of antisynthetase syndrome (ASS) are heterogeneous.
This study was therefore undertaken to identify subgroups of ASS patients with similar …

… The characterization of both T and B cells was … B expression in lung NK cells was shown
by an NKp46 plus granzyme B double staining, using anti-NKp46 and anti–granzyme B (clone …

… Centrilobular and paraseptal emphysema predominating in the upper lobes (B). Ground-glass
opacities in a patchy distribution in nonspecific interstitial pneumonia (C), and reticular …

… Characteristic skeletal abnormalities: a) bilateral and symmetric cortical osteosclerosis of
the diaphyseal and metaphyseal parts of the long bones on X-rays, and/or b) symmetric and …

Erdheim-Chester disease (ECD) is a rare form of non-Langerhans histiocytosis, with
noncodified therapeutic management and high mortality. No treatment has yet been shown to …

Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis.
BRAF V600E gain-of-function mutations have been observed in 57% of cases of Langerhans …

Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis.
BRAF mutations have been observed in Langerhans cell histiocytosis (LCH). We investigated …

… (A, B) Aortic involvement is characterized by a thickening of the aortic wall, initially described
as … (B) Quantitative assessment by surface of infiltration of descending aorta is shown for …

… In each of the anti-HMGCR-associated myopathy biopsies, necrosis appeared out of
proportion to the minimal lymphocytic infiltration, suggesting a lesser role of T and B cells in the …

… + CD56 dim NK cells in patients with chronic hepatitis B virus (HBV) or hepatitis C virus (… ,
expressed high amounts of granzyme B and exhibited polyfunctional responses (CD107a, IFN-…