User profiles for B. W. Kirkham
Bruce KirkhamProfessor of Translational Research, Kings College London Verified email at gstt.nhs.uk Cited by 18051 |
Interleukin‐17A: a unique pathway in immune‐mediated diseases: psoriasis, psoriatic arthritis and rheumatoid arthritis
BW Kirkham, A Kavanaugh, K Reich - Immunology, 2014 - Wiley Online Library
… Dr Kirkham has served as a consultant and/or advisory board member and/or acted as
paid speaker and/or participated in clinical trials for the following companies: Abbott, BMS, …
paid speaker and/or participated in clinical trials for the following companies: Abbott, BMS, …
The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies
DG McGonagle, IB McInnes, BW Kirkham… - Annals of the …, 2019 - ard.bmj.com
Although the pathogenic mechanisms underlying axial spondyloarthritis (axSpA) and
psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that immune …
psoriatic arthritis (PsA) are not fully elucidated, several lines of evidence suggest that immune …
IL-17 in the immunopathogenesis of spondyloarthritis
…, U Srenathan, LA Burns, BW Kirkham - Nature Reviews …, 2018 - nature.com
Spondyloarthritis (SpA) is a term that refers to a group of inflammatory diseases that includes
psoriatic arthritis, axial SpA and nonradiographic axial SpA, reactive arthritis, enteropathic …
psoriatic arthritis, axial SpA and nonradiographic axial SpA, reactive arthritis, enteropathic …
Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two‐year prospective study (the DAMAGE study cohort)
BW Kirkham, MN Lassere, JP Edmonds… - Arthritis & …, 2006 - Wiley Online Library
… -1β and TNFα, both at the mRNA level (weakly) in the present study and as secreted protein
in in vitro synovial membrane cultures (Kirkham BW, Juhasz KM: unpublished observations). …
in in vitro synovial membrane cultures (Kirkham BW, Juhasz KM: unpublished observations). …
Prospective evaluation of magnetic resonance imaging and physical examination findings in patients with greater trochanteric pain syndrome
…, SP Oakley, R Shnier, BW Kirkham - Arthritis & Rheumatism …, 2001 - Wiley Online Library
Objective This study examined patients with greater trochanteric pain syndrome (GTPS) to
determine the prevalence of gluteus medius pathology by utilizing magnetic resonance …
determine the prevalence of gluteus medius pathology by utilizing magnetic resonance …
Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin‐17 receptor IgG1 Fc fusion protein
…, KM Farmer, JS Walker, BW Kirkham - Arthritis & …, 2002 - Wiley Online Library
Objective To investigate the role of interleukin‐17 (IL‐17) in inflammatory arthritis by
blockade with an IL‐17 receptor/human IgG1 Fc fusion protein (muIL‐17R:Fc) in adjuvant‐induced …
blockade with an IL‐17 receptor/human IgG1 Fc fusion protein (muIL‐17R:Fc) in adjuvant‐induced …
[PDF][PDF] Interleukin‐17+ CD8+ T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression
… Taams and Kirkham contributed equally to this work. Dr. Garood has received consulting
fees… Kirkham has received consulting fees from Novartis (less than $10,000) and speaking fees …
fees… Kirkham has received consulting fees from Novartis (less than $10,000) and speaking fees …
In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses
Th17 cells are a recently defined subset of proinflammatory T cells that contribute to pathogen
clearance and tissue inflammation by means of the production of their signature cytokine IL…
clearance and tissue inflammation by means of the production of their signature cytokine IL…
Primary Sjögren's syndrome as a systemic disease: a study of participants enrolled in an international Sjögren's syndrome registry
…, Y Dong, P Helin, BW Kirkham… - Arthritis care & …, 2012 - Wiley Online Library
Objective To study the prevalence of extraglandular manifestations in primary Sjögren's
syndrome (SS) among participants enrolled in the Sjögren's International Collaborative Clinical …
syndrome (SS) among participants enrolled in the Sjögren's International Collaborative Clinical …
Comparison of three screening tools to detect psoriatic arthritis in patients with psoriasis (CONTEST study)
…, L Kay, S Kelly, BW Kirkham… - British Journal of …, 2013 - academic.oup.com
Background Multiple questionnaires to screen for psoriatic arthritis (PsA) have been developed
but the optimal screening questionnaire is unknown. Objectives To compare three PsA …
but the optimal screening questionnaire is unknown. Objectives To compare three PsA …