Background The Signal Transducer and Activator of Transcription 1 (STAT1) has traditionally
been regarded as a transmitter of interferon signaling and a pro-apoptotic tumour …

Endothelium‐derived microparticles (EMPs) are small vesicles released from endothelial
cells in response to cell injury, apoptosis, or activation. Elevated concentrations of EMPs have …

Neuromodulin (formerly designated P-57) is an abundant, neural specific, calmodulin-binding
protein which exhibits higher affinity for calmodulin in the absence of free Ca2+ than in the …

Objective Articular cartilage vesicles (ACVs) are extracellular organelles found in normal
articular cartilage. While they were initially defined by their ability to generate pathologic …

Primary Congenital Glaucoma (PCG) is an autosomal recessive disease caused by an abnormal
development of the anterior chamber angle. Although, PCG has been linked to several …

Pseudomonas aeruginosa causes life‐threatening infections in compromised and cystic
fibrosis patients. Pathogenesis stems from a number of virulence factors, including four type III …

A Ca(2+)-calmodulin dependent histone 3 kinase was partially purified from a low salt (150
mM NaCl) nuclear extract of mouse leukemia cells by calmodulin-Sepharose affinity …

Excess superoxide (O 2 − ) and nitric oxide (NO) forms peroxynitrite (ONOO − ) during
cardiac ischemia reperfusion (IR) injury, which in turn induces protein tyrosine nitration (tyr-N). …

Purpose : Ureteropelvic junction obstruction may either worsen and require surgery, improve
or remain stable. It may take upward of 3 years for the natural history to unfold. Urinary …

Polyclonal antibodies raised against bovine brain P-57, a neural-specific calmodulin-binding
protein, were used to isolate murine cDNAs encoding P-57 from murine brain cDNA …