Are there differences between young-and older-onset early inflammatory arthritis and do these impact outcomes? An analysis from the CATCH cohort
MB Arnold, VP Bykerk, G Boire, BP Haraoui… - …, 2014 - academic.oup.com
Objective. The aim of this study was to determine the impact of age on disease and remission
in suspected early RA (ERA). Methods. Data from the Canadian Early Arthritis Cohort (…
in suspected early RA (ERA). Methods. Data from the Canadian Early Arthritis Cohort (…
Incidence and predictors of secondary fibromyalgia in an early arthritis cohort
Objectives Secondary fibromyalgia (FM) is common among patients with inflammatory
arthritis, but little is known about its incidence and the factors leading to its development. The …
arthritis, but little is known about its incidence and the factors leading to its development. The …
Anticitrullinated protein antibodies and rheumatoid factor fluctuate in early inflammatory arthritis and do not predict clinical outcomes
L Barra, V Bykerk, JE Pope, BP Haraoui… - The Journal of …, 2013 - jrheum.org
Objective. In inflammatory arthritis, rheumatoid factor (RF) and anticitrullinated protein
antibodies (ACPA) are believed to be associated with more severe clinical outcomes. Our …
antibodies (ACPA) are believed to be associated with more severe clinical outcomes. Our …
Comparison of anti-TNF treatment initiation in rheumatoid arthritis databases demonstrates wide country variability in patient parameters at initiation of anti-TNF …
…, J Widdifield, JC Thorne, BP Haraoui… - Seminars in arthritis and …, 2011 - Elsevier
OBJECTIVE:: Characteristics of Canadian RA patients started on anti-tumor necrosis factor (TNF)
treatment were compared with 12 other countries. METHODS:: Data from the …
treatment were compared with 12 other countries. METHODS:: Data from the …
[HTML][HTML] The relationship between function and disease activity as measured by the HAQ and DAS28 varies over time and by rheumatoid factor status in early …
…, C Thorne, G Boire, C Hitchon, BP Haraoui… - The open …, 2013 - ncbi.nlm.nih.gov
Objective: To investigate the relationship between function and disease activity in early
inflammatory arthritis (EIA). Methods: Canadian Early Arthritis Cohort (CATCH)(n= 1143) is a multi…
inflammatory arthritis (EIA). Methods: Canadian Early Arthritis Cohort (CATCH)(n= 1143) is a multi…
Physician global assessment at 3 months is strongly predictive of remission at 12 months in early rheumatoid arthritis: results from the CATCH cohort
T Choy, VP Bykerk, G Boire, BP Haraoui… - …, 2014 - academic.oup.com
Objective. The objective of this study was to determine predictors of 1-year remission in early
RA (ERA) using baseline and 3-month data. Methods. The Canadian Early Arthritis Cohort (…
RA (ERA) using baseline and 3-month data. Methods. The Canadian Early Arthritis Cohort (…
Canadian Variation by Province in Rheumatoid Arthritis Initiating Anti–Tumor Necrosis Factor Therapy: Results from the Optimization of Adalimumab Trial
C Pease, JE Pope, C Thorne, BP Haraoui… - The Journal of …, 2010 - jrheum.org
Objective. We compared variations among Canadian provinces in rheumatoid arthritis (RA)
initiating anti-tumor necrosis factor (TNF) therapy. Methods. Data were obtained from the …
initiating anti-tumor necrosis factor (TNF) therapy. Methods. Data were obtained from the …
[HTML][HTML] Do patients with active RA have differences in disease activity and perceptions if anti-TNF naďve versus anti-TNF experienced? Baseline results of the …
J Pope, JC Thorne, BP Haraoui… - … medical journal of …, 2012 - ncbi.nlm.nih.gov
Background The chance of a good response in RA is attenuated in previous anti-TNF users
who start new anti-TNF therapy compared to biologic naďve patients. In active RA, those with …
who start new anti-TNF therapy compared to biologic naďve patients. In active RA, those with …
Does C-reactive protein add value in active rheumatoid arthritis? Results from the Optimization of Humira Trial
JE Pope, C Thorne, BP Haraoui, D Truong… - Scandinavian journal …, 2011 - Taylor & Francis
Tumour necrosis factor (TNF)-α can stimulate an acutephase response leading to the synthesis
of acute-phase proteins such as C-reactive protein (CRP). High levels of CRP are often …
of acute-phase proteins such as C-reactive protein (CRP). High levels of CRP are often …
Arthritis clinical trials at a crossroad
JE Pope, JC Thorne, BP Haraoui, J Karsh… - The Journal of …, 2015 - jrheum.org
With more than a century of combined trial experience, we discuss the demise of pharmaceutical
company inflammatory arthritis clinical trials, speaking from our experience in Canada …
company inflammatory arthritis clinical trials, speaking from our experience in Canada …