Melanoma originates in the epidermis and becomes metastatic after invasion into the dermis.
Prior interactions between melanoma cells and dermis are poorly studied. Here, we show …

Blistering skin diseases are a group of autoimmune disorders that are characterized by
autoantibodies against structural proteins of the epidermis or the dermal–epidermal junction and …

Background: Familial Mediterranean fever (FMF) is an autosomal recessive disease that
tends to affect certain ethnic groups. It is characterized by recurrent, self-limited attacks of …

Background It is generally accepted that folliculotropic mycosis fungoides (FMF) is usually
typified by indurated plaques and tumors mainly on the head/neck and an aggressive course. …

Background Unlike T-cell neoplasms, B-cell lymphoproliferative disorders have a limited
clinical spectrum of skin involvement. Cutaneous B-cell neoplasms mimicking rosacea or …

The E-cadherin-beta-catenin complex regulates the architectural integrity of epithelia by
mediating intercellular adhesion. Down-regulation of its expression may contribute to invasion …

Vascular anomalies (VAs) may be associated with significant morbidity and mortality. The
aim of this study was to evaluate the efficacy and safety of sirolimus (rapamycin) in the …

Background Metastatic melanoma is a devastating disease with limited therapeutic options.
MicroRNAs (miRNAs) are small non coding RNA molecules with important roles in post-…

Background Psoriasis is a complex disease at the cellular, genomic and genetic levels. The
role of microRNAs in skin development was shown in a keratinocyte-specific Dicer knockout …

Background Exaggerated reaction to insect bites, mainly to mosquitoes, is infrequently
described in patients with chronic lymphocytic leukemia. Skin lesions usually appear months to …