OBJECTIVE: We hypothesize that androgen deficiency is a critical etiologic factor in the
pathogenesis of aqueous-deficient and evaporative dry eye in Sjögren's syndrome (SS). We …

Background: Sjögren’s syndrome is characterized by the presence of xerostomia and/or
xerophthalmia. Pilocarpine, a muscarinic cholinergic agonist, has been proven to be efficacious …

In Part I of this study, the Human Nutrition Research Center of the United States Department
of Agriculture's Nutritional Status Study (NSS) of 691 independently living elderly people …

Background Primary Sjögren's syndrome is an autoimmune disease that presents as dryness
of the mouth and eyes due to impairment of the exocrine glands. To our knowledge, no …

Background The authors conducted two multicenter, randomized, double-blinded, controlled
Phase III clinical trials to study the efficacy and safety of phentolamine mesylate (PM) in …

Purpose: We hypothesized that women with primary (pSS) and secondary Sjögren
syndrome (sSS; with systemic lupus erythematosus [SLE] or rheumatoid arthritis [RA]) have …

… Papas DMD, PhD 9 , Soft Tissue Anesthesia Reversal Group … Papas and Goodson are
members of the Clinical Advisory Board for Novalar Pharmaceuticals. Drs. Tavares, Gordon and …

Phentolamine mesylate accelerates recovery from oral soft tissue anesthesia in patients
who have received local anesthetic injections containing a vasoconstrictor. The proposed …

Poor oral health can profoundly decrease appetite and the ability to eat, which in turn may
lead to poor nutrition. Compromised nutritional status may result in an impaired immune …

Background: Non‐steroidal anti‐inflammatory agents inhibit the production of cyclooxygenase
(COX) products and can attenuate bone loss. In this double‐masked, placebo‐controlled, …