Human peripheral blood monocytes have high affinity binding sites for 1,25-(OH) 2 D 3 (Kd
0.14 nM, sedimentation coefficient 3.7S). Resting human peripheral blood T lymphocytes, …

Patients with severe ankylosing spondylitis of long duration often have spinal osteoporosis
secondary to ankylosis and immobility. Bone mineral density of defined regions of the lumbar …

The proliferative response of murine spleen and thymus cells to antigen but not to lectin was
inhibited by the active metabolite of vitamin D3, 1,25-(OH)2D3. To directly examine the …

Human peripheral blood monocytes and activated, but not resting, lymphocytes possess
specific intracellular receptors for the active metabolite of vitamin D 3 , 1,25-dihydroxyvitamin D …

Objective Vertebral osteophytes are a characteristic feature of intervertebral disc degeneration.
There are, however, few population data concerning the occurrence of and clinico-…

Introduction The pathology of ankylosing spondylitis (AS) suggests that certain cytokines and
matrix metalloproteinases (MMPs) might provide useful markers of disease activity. Serum …

OBJECTIVE: To assess bone mineral density (BMD) by dual energy x-ray absorptiometry (DEXA)
and calcaneal quantitative ultrasound (QUS) in a cohort of pre- and postmenopausal …

There is no agreed definition of osteoporosis in pre-menopausal women. The International
Society for Clinical Densitometry recommends using Z-score, and women with Z-scores of −…

Objectives. To assess the prevalences across Europe of radiological indices of degenerative
inter-vertebral disc disease (DDD); and to quantify their associations with, age, sex, …

The vitamin D endocrine system is crucial in clacium homeostasis in mammalian species.
Central to this role 1,25-dihydroxyvitamin D-3 (1,25-(OH) 2 D 3 ) receptors have been detected …