[HTML][HTML] Mucosal-associated invariant T cells in autoimmune diseases
A Chiba, G Murayama, S Miyake - Frontiers in immunology, 2018 - frontiersin.org
Mucosal-associated invariant T (MAIT) cells are innate T cells restricted by MHC-related
molecule 1 (MR1). MAIT cells express semi-invariant T-cell receptors TRAV1-2-TRAJ33/12/20 in …
molecule 1 (MR1). MAIT cells express semi-invariant T-cell receptors TRAV1-2-TRAJ33/12/20 in …
[HTML][HTML] Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis–Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria
I Sada-Ovalle, A Chiba, A Gonzales, MB Brenner… - PLoS …, 2008 - journals.plos.org
Cellular immunity to Mycobacterium tuberculosis (Mtb) requires a coordinated response
between the innate and adaptive arms of the immune system, resulting in a type 1 cytokine …
between the innate and adaptive arms of the immune system, resulting in a type 1 cytokine …
[HTML][HTML] The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells
S Oki, A Chiba, T Yamamura… - The Journal of clinical …, 2004 - Am Soc Clin Investig
OCH, a sphingosine-truncated analog of α-galactosylceramide (αGC), is a potential
therapeutic reagent for a variety of Th1-mediated autoimmune diseases through its selective …
therapeutic reagent for a variety of Th1-mediated autoimmune diseases through its selective …
[HTML][HTML] The dual role of short fatty acid chains in the pathogenesis of autoimmune disease models
M Mizuno, D Noto, N Kaga, A Chiba, S Miyake - PloS one, 2017 - journals.plos.org
Autoimmune diseases are influenced by both genetic and environmental factors. The gut
environment has attracted much attention as an essential component that modulates immune …
environment has attracted much attention as an essential component that modulates immune …
Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis
Y Miyazaki, S Miyake, A Chiba, O Lantz… - International …, 2011 - academic.oup.com
Mucosal-associated invariant T (MAIT) cells are innate T cells expressing an invariant Vα7.2-Jα33
T-cell antigen receptor α chain and are enriched in mucosal-associated lymphoid …
T-cell antigen receptor α chain and are enriched in mucosal-associated lymphoid …
Resolution of one-year persisting COVID-19 pneumonia and development of immune thrombocytopenia in a follicular lymphoma patient with preceding rituximab …
H Yasuda, Y Mori, A Chiba, J Bai, G Murayama… - … Myeloma and Leukemia, 2021 - Elsevier
Background We previously reported elsewhere of a follicular lymphoma patient suffering
from persistent COVID-19 pneumonia that was still ongoing at 2 months after onset. Materials …
from persistent COVID-19 pneumonia that was still ongoing at 2 months after onset. Materials …
Mucosal‐associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis
A Chiba, R Tajima, C Tomi, Y Miyazaki… - Arthritis & …, 2012 - Wiley Online Library
Objective The function of mucosal‐associated invariant T (MAIT) cells remains largely
unknown. We previously reported an immunoregulatory role of MAIT cells in an animal model of …
unknown. We previously reported an immunoregulatory role of MAIT cells in an animal model of …
MAIT cells are activated and accumulated in the inflamed mucosa of ulcerative colitis
K Haga, A Chiba, T Shibuya, T Osada… - Journal of …, 2016 - Wiley Online Library
Background and Aim: Ulcerative colitis (UC) is a chronic, relapsing and remitting, inflammatory
disorder of the large intestine. Mucosal associated invariant T (MAIT) cells are a member …
disorder of the large intestine. Mucosal associated invariant T (MAIT) cells are a member …
Suppression of collagen‐induced arthritis by natural killer T cell activation with OCH, a sphingosine‐truncated analog of α‐galactosylceramide
A Chiba, S Oki, K Miyamoto… - … : Official Journal of …, 2004 - Wiley Online Library
Objective OCH, a synthetic analog of α‐galactosylceramide with a truncated sphingosine
chain, stimulates natural killer T (NKT) cells to produce predominantly Th2 cytokines. Thus, …
chain, stimulates natural killer T (NKT) cells to produce predominantly Th2 cytokines. Thus, …
[PDF][PDF] Innate recognition of cell wall β-glucans drives invariant natural killer T cell responses against fungi
…, RVV Tatituri, A Rivera, GFM Watts, EY Kim, A Chiba… - Cell host & …, 2011 - cell.com
iNKT cells are innate T lymphocytes recognizing endogenous and foreign lipid antigens
presented in the MHC-like molecule CD1d. The semi-invariant iNKT cell TCR can detect certain …
presented in the MHC-like molecule CD1d. The semi-invariant iNKT cell TCR can detect certain …